{"id":"W2839226594","doi":"10.1038/s41598-018-28717-y","title":"Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; U.S. Department of Health and Human Services; National Institutes of Health; National Institute of General Medical Sciences; Wellcome Trust; Institute of Genetics; School of Medicine, Boston University","keywords":"Melanoma; Cancer research; Metastasis; Cell migration; Biology; Filopodia; Microphthalmia-associated transcription factor; Myosin; Gene silencing; Cell biology; Actin; Cell culture; Cancer; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007898138,0.0003346555,0.0001125386,0.0001474761,0.0001797337,0.0002320373,0.0001622264,0.0002740572,0.001863148],"category_scores_gemma":[0.00007454805,0.0002046066,0.0001401365,0.00005827465,0.0001914369,0.0001359635,0.0002927277,0.0003102134,0.000706578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000273257,"about_ca_system_score_gemma":0.0002027384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008133158,"about_ca_topic_score_gemma":0.001293701,"domain_scores_codex":[0.9999132,0.00000954764,0.000006691542,0.0000226779,0.00002077197,0.00002707719],"domain_scores_gemma":[0.9998678,0.0000111799,0.00005014224,0.000009054696,0.000008576083,0.00005321039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004463816,0.000007404854,0.0003239344,0.00001168257,0.000001528824,0.00005051312,0.000003302339,0.00001464304,0.999159,0.00006454235,0.00002376669,0.0002950221],"study_design_scores_gemma":[0.00002680151,0.0001465118,0.0371022,0.00001334812,0.00001244967,0.0005549894,0.0000539503,0.001440968,0.9566938,0.0001113018,0.003838213,0.000005473765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958475,0.0008901525,0.001591541,0.00005173507,0.00002027326,0.00001011743,0.0002223932,0.00007985604,0.001286405],"genre_scores_gemma":[0.9953302,0.0002829666,0.000737822,0.00001838999,0.000003703256,0.00001253651,0.0003271377,0.00002333122,0.00326407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001863148,"threshold_uncertainty_score":0.006232858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01560909996511431,"score_gpt":0.2620276622760871,"score_spread":0.2464185623109728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}