{"id":"W2839463924","doi":"10.1016/j.cellimm.2018.07.001","title":"Autocrine GABA signaling distinctively regulates phenotypic activation of mouse pulmonary macrophages","year":2018,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Autocrine signalling; Phenotype; Biology; Cell biology; Signal transduction; Receptor; Phenotypic switching; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001259131,0.0002521788,0.0002204194,0.0004661837,0.0001551678,0.0003685371,0.0001794665,0.0002704428,0.001024201],"category_scores_gemma":[0.00008850609,0.0001594168,0.000240717,0.0001425082,0.0002409287,0.0001994602,0.0002325972,0.0006622404,0.0003532513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001793562,"about_ca_system_score_gemma":0.0001182124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002083375,"about_ca_topic_score_gemma":0.0005579628,"domain_scores_codex":[0.9997241,0.00005075567,0.00001945741,0.00005094513,0.00004368103,0.0001110285],"domain_scores_gemma":[0.9998928,0.00001305484,0.00002943368,0.00001568545,0.00001334448,0.00003562864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001485828,0.00001379523,0.0002491979,0.000008552143,0.000001661056,0.00005809276,0.0000118707,0.00001084038,0.9989364,0.00008756325,0.0000125184,0.0004609764],"study_design_scores_gemma":[0.00003390933,0.0002181478,0.01712661,0.00001135273,0.00002795313,0.0005351663,0.0001874229,0.0005072649,0.9794967,0.0002080579,0.001641164,0.000006482352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956911,0.00114667,0.00136846,0.00009048852,0.00002313774,0.00001049783,0.0001646196,0.00004050836,0.00146443],"genre_scores_gemma":[0.9970738,0.0004505262,0.0006885919,0.00005865279,0.00001059657,0.00002064343,0.0001381572,0.00002291719,0.001536188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001024201,"threshold_uncertainty_score":0.003426254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01823272335973868,"score_gpt":0.2344122135494995,"score_spread":0.2161794901897608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}