{"id":"W2839463924","doi":"10.1016/j.cellimm.2018.07.001","title":"Autocrine GABA signaling distinctively regulates phenotypic activation of mouse pulmonary macrophages","year":2018,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Autocrine signalling; Phenotype; Biology; Cell biology; Signal transduction; Receptor; Phenotypic switching; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008279502,0.0001715928,0.0002160857,0.0001378083,0.0001739869,0.00001553553,0.000327161,0.0001056394,0.0004294272],"category_scores_gemma":[0.0003051083,0.0001640277,0.00007056896,0.0002986253,0.0007747025,0.0001464506,0.0001350524,0.0001528718,0.0001254666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003057296,"about_ca_system_score_gemma":0.00003247092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000211388,"about_ca_topic_score_gemma":0.000001068923,"domain_scores_codex":[0.9987128,0.0001648257,0.0002723936,0.0003973143,0.0001308303,0.0003218169],"domain_scores_gemma":[0.9992142,0.000175755,0.0001836931,0.0003378617,0.00005737215,0.0000310757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001812642,0.0001364108,0.00006745972,0.00001881858,0.00001441121,0.00001103833,0.0002020033,0.00001133305,0.9925036,0.003005627,0.00002970522,0.003818335],"study_design_scores_gemma":[0.0003747446,0.0001884724,0.002532188,0.0000162636,0.000006197205,0.00001173788,0.0001092322,0.0004044384,0.9925143,0.00281761,0.0008664394,0.0001583617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952071,0.0002354747,0.002391886,0.0001791985,0.0002215916,0.0001897989,0.00001091665,0.000117822,0.001446251],"genre_scores_gemma":[0.9980028,0.00001853892,0.0002030656,0.0001073719,0.00007999498,0.00001117598,0.00001220551,0.00002901555,0.001535794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003659973,"threshold_uncertainty_score":0.6688857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01823272335973868,"score_gpt":0.2344122135494995,"score_spread":0.2161794901897608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}