{"id":"W2854829954","doi":"10.1128/jvi.00157-18","title":"Characterization of the Plasmacytoid Dendritic Cell Response to Transmitted/Founder and Nontransmitted Variants of HIV-1","year":2018,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Mount Sinai Hospital; Centre for Advancing Health Outcomes; University of British Columbia; University of Toronto","funders":"Government of Canada; National Institutes of Health; Canadian Institutes of Health Research; National Institute of Allergy and Infectious Diseases; Ontario HIV Treatment Network; Kaohsiung Medical University","keywords":"Biology; Virology; Virus; Secretion; Founder effect; Human immunodeficiency virus (HIV); Genetics; Immunology; Gene; Haplotype; Allele","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001784812,0.0001152771,0.0001739112,0.0002148759,0.0001311577,0.0003328292,0.0001290157,0.0002816058,0.0009064586],"category_scores_gemma":[0.0002533676,0.00007153121,0.0001512149,0.0001520541,0.0001384859,0.000180044,0.0001713479,0.0005369313,0.0002285461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001499736,"about_ca_system_score_gemma":0.0001375638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002165224,"about_ca_topic_score_gemma":0.000211573,"domain_scores_codex":[0.9998633,0.00002053178,0.0000130351,0.00003211574,0.00003073494,0.00004036357],"domain_scores_gemma":[0.9998378,0.00004261512,0.00001683756,0.00002142521,0.0000327954,0.00004864536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001774866,0.0000476404,0.003054904,0.00002203919,0.000003883285,0.00009665402,0.00007402252,0.00004160091,0.9948147,0.00005474212,0.00001558622,0.001596546],"study_design_scores_gemma":[0.000129827,0.003298334,0.1670182,0.00004129844,0.00009975849,0.003334211,0.001091541,0.003413068,0.8164446,0.0004061594,0.004702592,0.0000205099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989169,0.0001659118,0.0004139068,0.00001049614,0.000004824863,0.00002115018,0.0001083847,0.000003365619,0.0003551297],"genre_scores_gemma":[0.997831,0.0002403618,0.0008874701,0.00004170875,0.00001487021,0.00004509684,0.0003454924,0.000005516148,0.0005884447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009064586,"threshold_uncertainty_score":0.003032446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008159469136393406,"score_gpt":0.2360734539097539,"score_spread":0.2279139847733605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}