{"id":"W2873176665","doi":"10.1074/jbc.ra118.002767","title":"Kinesin-2 heterodimerization alters entry into a processive run along the microtubule but not stepping within the run","year":2018,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Medicine Hat College","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Rensselaer Polytechnic Institute","keywords":"Kinesin; Microtubule; Biophysics; Molecular motor; Cell biology; Processivity; Motor protein; Biology; Kinetics; Chemistry; Biochemistry; DNA; Physics; Polymerase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001796295,0.0002753904,0.0001527143,0.0001023333,0.0001497597,0.0003318539,0.0002096635,0.0002174248,0.001542958],"category_scores_gemma":[0.0001904555,0.0001596508,0.000249132,0.00009307596,0.0001932642,0.0002084674,0.0001413836,0.0005166521,0.000222136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003033781,"about_ca_system_score_gemma":0.0001970138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008123183,"about_ca_topic_score_gemma":0.0009817446,"domain_scores_codex":[0.9998907,0.00001758135,0.00001010491,0.0000335215,0.00002872986,0.00001929135],"domain_scores_gemma":[0.9998903,0.0000386772,0.00002774916,0.00001370893,0.000009298299,0.00002014704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001250667,0.00004841659,0.0005361795,0.00001565848,0.00001126101,0.00003677647,0.00001467495,0.0006719411,0.9972469,0.000507011,0.00002750873,0.0007586277],"study_design_scores_gemma":[0.00002242732,0.0001436987,0.006011217,0.000004026992,0.00001750881,0.0001390536,0.00004619209,0.01771534,0.9741876,0.0002840748,0.00141795,0.00001095803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962925,0.0001069938,0.002764182,0.00002939995,0.00001310358,0.000007699855,0.00008621426,0.00004503516,0.0006548258],"genre_scores_gemma":[0.9983709,0.00005295333,0.0009108806,0.00001184854,0.00000102235,0.000009356326,0.00008705487,0.000020473,0.0005354845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001542958,"threshold_uncertainty_score":0.005161703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01129981741825088,"score_gpt":0.242415348312698,"score_spread":0.2311155308944471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}