{"id":"W2873674548","doi":"10.1016/j.ceca.2018.07.002","title":"Heterogeneity of calcium clock functions in dormant, dysrhythmically and rhythmically firing single pacemaker cells isolated from SA node","year":2018,"lang":"en","type":"article","venue":"Cell Calcium","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Stimulation; Sinoatrial node; Rhythm; Biology; Diastolic depolarization; Biophysics; Neuroscience; Internal medicine; Endocrinology; Heart rate; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000139295,0.0002827835,0.0006457441,0.0001448328,0.000101639,0.00001484582,0.00005264237,0.0003322109,0.0001738194],"category_scores_gemma":[0.00004457215,0.0002609408,0.0001863783,0.0003002321,0.0003749013,0.00008331316,0.0001316595,0.0004363424,0.000132805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000891501,"about_ca_system_score_gemma":0.0000923948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001334098,"about_ca_topic_score_gemma":0.00006613673,"domain_scores_codex":[0.9981228,0.0001071626,0.0005169379,0.0005497715,0.0001871354,0.0005162595],"domain_scores_gemma":[0.9988295,0.000152607,0.0001406777,0.0004946803,0.0001656014,0.0002169183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001013284,0.0002171592,0.002778576,0.00006160004,0.00007371954,0.0002582028,0.000198285,0.00003836976,0.9939145,0.000009430413,0.0009666375,0.0004702428],"study_design_scores_gemma":[0.003142026,0.00131581,0.0673161,0.0001651193,0.000222469,0.0003152623,0.00005398963,0.002637561,0.9211872,0.0001171109,0.003087064,0.0004402846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938728,0.0006743043,0.002387163,0.0002974615,0.0004534565,0.0003189881,0.00005569351,0.00006554271,0.001874653],"genre_scores_gemma":[0.997466,0.00003326616,0.0006534207,0.0005393748,0.0006560461,0.00001291172,0.00005695452,0.00004046998,0.0005415938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07272729,"threshold_uncertainty_score":0.9999843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01806661490792699,"score_gpt":0.2550507232158581,"score_spread":0.2369841083079312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}