{"id":"W287525851","doi":"10.1023/a:1007053802481","title":"Sarco/endoplasmic reticulum Ca2+-pump isoform SERCA3a is more resistant to superoxide damage than SERCA2b","year":2000,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Superoxide; Xanthine oxidase; Chemistry; Catalase; Reactive oxygen species; Biochemistry; Hydrogen peroxide; Microsome; Gene isoform; NADPH oxidase; Peroxide; Superoxide dismutase; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001862407,0.000399885,0.0002511519,0.00006132402,0.0002009026,0.00008403078,0.0002507372,0.0003841248,0.0003957168],"category_scores_gemma":[0.00003653518,0.0004125365,0.0001966065,0.000213821,0.0001304862,0.000009170079,0.0001307244,0.0001814069,0.00006253743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003728271,"about_ca_system_score_gemma":0.00007540904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004581833,"about_ca_topic_score_gemma":0.000006434606,"domain_scores_codex":[0.9978625,0.00005134169,0.00034567,0.0008450064,0.0003244587,0.0005710096],"domain_scores_gemma":[0.9986733,0.000005682387,0.00005811887,0.0007378988,0.0001114095,0.000413589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002507458,0.00006361843,0.0002779889,0.00006648945,0.00006074281,0.00004472089,0.0001059704,0.00006257112,0.9958596,0.00003000898,0.002441453,0.0007360611],"study_design_scores_gemma":[0.0006765209,0.0001740254,0.0002020225,0.00003903879,0.00004294554,0.00005436236,0.0003264368,0.0002098665,0.9684156,0.00004232521,0.02931437,0.0005024404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923853,0.0005978259,0.0009575821,0.001287711,0.0001251446,0.0002690672,0.00008025852,0.00004697288,0.004250102],"genre_scores_gemma":[0.9848692,0.00005840981,0.0003380566,0.001958345,0.0002614334,0.00003477015,0.0006621004,0.00006566794,0.01175203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02744399,"threshold_uncertainty_score":0.9998326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004561357890532263,"score_gpt":0.2065781117061371,"score_spread":0.2020167538156048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}