{"id":"W2875754447","doi":"10.1128/mbio.01136-18","title":"HtrA of Borrelia burgdorferi Leads to Decreased Swarm Motility and Decreased Production of Pyruvate","year":2018,"lang":"en","type":"article","venue":"mBio","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Medical College of Wisconsin; National Institutes of Health; Stony Brook University; University of Saskatchewan","keywords":"Borrelia burgdorferi; Biochemistry; Proteome; Pyruvate kinase; Biology; Proteomics; Dehydrogenase; Enzyme; Glycolysis; Chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002134662,0.0001527709,0.0002970779,0.0001192811,0.00008418905,0.000004773683,0.0001150144,0.0001411602,0.0003267338],"category_scores_gemma":[0.000562296,0.0001446354,0.00006868106,0.0002156875,0.0005086921,0.00004586915,0.00005771979,0.00008757148,0.00009515182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002987494,"about_ca_system_score_gemma":0.00009045949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001059603,"about_ca_topic_score_gemma":0.0001947926,"domain_scores_codex":[0.9989589,0.0001217176,0.0003045604,0.0003412973,0.00003951335,0.000234028],"domain_scores_gemma":[0.9990955,0.00005399593,0.0001297219,0.0004019274,0.000259989,0.00005887134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004049396,0.0003530484,0.1661811,0.00005330347,0.00009268014,5.395941e-7,0.0002172002,0.000002104568,0.8292601,0.00006444545,0.002019042,0.001351602],"study_design_scores_gemma":[0.0004642794,0.0004146585,0.3880851,0.00003137028,0.0000606162,0.000007897594,0.00002964857,0.000001269323,0.60968,0.00008755711,0.001053291,0.00008431845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997972,0.0004381261,0.00006554165,0.0001253421,0.0006324861,0.0003302437,0.00005093919,0.00007285358,0.0003124648],"genre_scores_gemma":[0.9994624,0.0000128591,0.00008036395,0.00007962379,0.00005364669,0.00001593127,0.00003574858,0.00001445829,0.0002449807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2219041,"threshold_uncertainty_score":0.5898061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01084311092677068,"score_gpt":0.245998150520656,"score_spread":0.2351550395938853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}