{"id":"W2877186102","doi":"10.1177/0022034518785164","title":"Protein Arginine Methyltransferase PRMT1 Is Essential for Palatogenesis","year":2018,"lang":"en","type":"article","venue":"Journal of Dental Research","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Dental and Craniofacial Research; National Natural Science Foundation of China; University of Southern California","keywords":"Biology; Protein arginine methyltransferase 5; Craniofacial; Neural crest; Methyltransferase; Cell biology; Signal transduction; Wnt signaling pathway; Epigenetics; Methylation; Genetics; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001439221,0.0004579996,0.0003884757,0.0002687054,0.00041706,0.0003964735,0.0003493072,0.0003576218,0.001820812],"category_scores_gemma":[0.0002732005,0.0001659215,0.0003161073,0.0002483418,0.0002332951,0.0002148939,0.0003969627,0.0004958896,0.001161714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003283597,"about_ca_system_score_gemma":0.0004141343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000823881,"about_ca_topic_score_gemma":0.0009339637,"domain_scores_codex":[0.9998048,0.00002106904,0.00001624075,0.00005867736,0.00007054019,0.00002871375],"domain_scores_gemma":[0.9998275,0.00001576811,0.00006697343,0.00001870157,0.00003024008,0.00004071833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009933893,0.0000204699,0.00206548,0.0001327768,0.00001257125,0.0004141634,0.00002783324,0.0000943323,0.9837695,0.000345993,0.0004093741,0.01260825],"study_design_scores_gemma":[0.00002845278,0.0002185412,0.03898784,0.0000318932,0.0000684065,0.004061177,0.00007456694,0.001358015,0.9095813,0.000678179,0.04489132,0.00002037342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9093073,0.04377995,0.03069609,0.001374865,0.0003842529,0.0001017326,0.003500897,0.002165247,0.008689649],"genre_scores_gemma":[0.9787198,0.006177462,0.00566774,0.00009832438,0.00003699655,0.00003066548,0.001704875,0.0001078369,0.007456298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001820812,"threshold_uncertainty_score":0.006091177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03657285985759346,"score_gpt":0.3952253447241274,"score_spread":0.3586524848665339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}