{"id":"W2877186102","doi":"10.1177/0022034518785164","title":"Protein Arginine Methyltransferase PRMT1 Is Essential for Palatogenesis","year":2018,"lang":"en","type":"article","venue":"Journal of Dental Research","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Dental and Craniofacial Research; National Natural Science Foundation of China; University of Southern California","keywords":"Biology; Protein arginine methyltransferase 5; Craniofacial; Neural crest; Methyltransferase; Cell biology; Signal transduction; Wnt signaling pathway; Epigenetics; Methylation; Genetics; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00101423,0.00008991041,0.0001327726,0.0001645817,0.0001268794,0.00003736432,0.000218249,0.0001386183,0.000107017],"category_scores_gemma":[0.0001645285,0.00007990681,0.0001695463,0.0001972061,0.0001622769,0.000008669075,0.00005383407,0.0001539201,0.00001178714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004685366,"about_ca_system_score_gemma":0.0002465912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001065257,"about_ca_topic_score_gemma":0.00003857862,"domain_scores_codex":[0.9986062,0.0001122849,0.0002996889,0.0001812118,0.0005218615,0.0002787592],"domain_scores_gemma":[0.9987512,0.0000227326,0.00009349004,0.0001759319,0.0008281796,0.0001284562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001026842,0.000071575,0.0004802714,0.00002228965,0.000112083,0.000003702264,0.00004173507,0.000007825029,0.9851657,0.00001698447,0.004646978,0.008404048],"study_design_scores_gemma":[0.001133202,0.00162131,0.0007264545,0.00003730702,0.00001985752,0.00006817046,0.00006313875,0.00008581911,0.971553,0.0001379664,0.0244712,0.0000825243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932609,0.0009635932,0.0046146,0.0004192974,0.0002001063,0.0003866015,0.00001894409,0.00000201836,0.0001339336],"genre_scores_gemma":[0.9956013,0.000160364,0.001204004,0.00002806405,0.00187864,0.00001920307,0.0000124127,0.00002405522,0.001071946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01982422,"threshold_uncertainty_score":0.3258505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03657285985759346,"score_gpt":0.3952253447241274,"score_spread":0.3586524848665339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}