{"id":"W2881027274","doi":"10.3390/ijms19072026","title":"Phosphokinome Analysis of Barth Syndrome Lymphoblasts Identify Novel Targets in the Pathophysiology of the Disease","year":2018,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; University of British Columbia; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Manitoba Health Research Council; Manitoba Medical Service Foundation; Research Manitoba; Children's Hospital Research Institute of Manitoba; Heart and Stroke Foundation of Canada","keywords":"Cardiolipin; Lymphoblast; Phosphorylation; Biology; Biochemistry; Phospholipid; Genetics; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006310319,0.00028913,0.0001255653,0.0004498355,0.0001370596,0.0002112425,0.0001049154,0.000263216,0.001322213],"category_scores_gemma":[0.0001351736,0.00009134258,0.000134965,0.0001872533,0.0001435053,0.0001551967,0.000151593,0.0001718361,0.0002829412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001170952,"about_ca_system_score_gemma":0.00006420568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002566962,"about_ca_topic_score_gemma":0.0003505178,"domain_scores_codex":[0.999958,0.000006150825,0.00000434846,0.00001248513,0.00001107557,0.000007921079],"domain_scores_gemma":[0.999933,0.00001613143,0.00002169776,0.000006128164,0.000007908538,0.00001517606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001347176,0.000003007107,0.001172116,0.00001634469,0.000004195382,0.0002862639,0.0000223079,0.00002090157,0.9975871,0.00004317094,0.00001186373,0.0006979768],"study_design_scores_gemma":[0.0000254911,0.0003375083,0.1185857,0.00001246244,0.0000458605,0.006482672,0.000181605,0.0008392089,0.8705966,0.0003814493,0.002500755,0.00001072318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972519,0.000582844,0.001333762,0.00004412362,0.00000869551,0.000007370808,0.0003487346,0.00002784208,0.0003947116],"genre_scores_gemma":[0.996436,0.0004917769,0.001680525,0.00002838217,0.000007082367,0.00001118616,0.000511886,0.00001053453,0.0008226251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001322213,"threshold_uncertainty_score":0.004423261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009797507940860414,"score_gpt":0.2820871981817487,"score_spread":0.2722896902408882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}