{"id":"W2882987303","doi":"10.3389/fcell.2018.00077","title":"Anaphase Chromosomes in Crane-Fly Spermatocytes Treated With Taxol (Paclitaxel) Accelerate When Their Kinetochore Microtubules Are Cut: Evidence for Spindle Matrix Involvement With Spindle Forces","year":2018,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Air Force Office of Scientific Research; Natural Sciences and Engineering Research Council of Canada; U.S. Air Force; David and Lucile Packard Foundation","keywords":"Kinetochore; Anaphase; Spindle checkpoint; Paclitaxel; Cell biology; Microtubule; Spindle pole body; Spindle apparatus; Chemistry; Biology; Chromosome; Genetics; Cell division; Cell; Chemotherapy; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005644145,0.0001859147,0.0001561734,0.0003148246,0.0002031215,0.0002871052,0.0001594913,0.0003035864,0.001720105],"category_scores_gemma":[0.00006052475,0.0001451194,0.0001702676,0.000185488,0.000176209,0.0001445691,0.0001186235,0.0004845691,0.0003876965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002712821,"about_ca_system_score_gemma":0.0001821186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003193899,"about_ca_topic_score_gemma":0.006357844,"domain_scores_codex":[0.9999337,0.000005855709,0.000005794182,0.00001971259,0.00001921462,0.00001565829],"domain_scores_gemma":[0.9998552,0.00002447924,0.00004866978,0.00001661743,0.00002340898,0.00003168658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005693822,0.000007960553,0.0003982534,0.00002451111,0.00000363348,0.00003978819,0.00001791818,0.000007699565,0.998874,0.00003725001,0.00002198042,0.0005099029],"study_design_scores_gemma":[0.00001957006,0.000141239,0.05436369,0.000006665091,0.00001493073,0.0002282605,0.00006841866,0.0002352104,0.9421027,0.00002915849,0.002785345,0.000004743032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927742,0.002598409,0.001434341,0.0001163667,0.0000308934,0.00003079738,0.0007377896,0.00004620449,0.002230853],"genre_scores_gemma":[0.9926615,0.001228285,0.001352902,0.00005976596,0.00000985367,0.00002841344,0.0007291331,0.00001872771,0.003911601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003193899,"threshold_uncertainty_score":0.006350577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01859288908054442,"score_gpt":0.252040793511561,"score_spread":0.2334479044310166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}