{"id":"W2883025207","doi":"10.1039/c8ob01463a","title":"Formation of <i>N</i><sup>α</sup>-terminal 2-dialkyl amino oxazoles from guanidinated derivatives under mild conditions","year":2018,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Population and Public Health; Secretaría de Estado de Investigación, Desarrollo e Innovación; Departament d'Innovació, Universitats i Empresa, Generalitat de Catalunya; National Research Foundation; National Science Foundation, United Arab Emirates; Inyuvesi Yakwazulu-Natali; King Saud University","keywords":"Oxazole; Chemistry; Intramolecular force; Residue (chemistry); Peptide; Amino acid; Stereochemistry; Combinatorial chemistry; Molecule; Organic chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008022221,0.0002724613,0.0002840473,0.00003259956,0.0001250237,0.00003475939,0.0003383393,0.0002930453,0.0009656452],"category_scores_gemma":[0.0001128699,0.0002721916,0.0002235433,0.0002698265,0.0003638356,0.00001346918,0.0001671453,0.00009599901,0.00003319462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003533328,"about_ca_system_score_gemma":0.00007029923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003333606,"about_ca_topic_score_gemma":0.000005604341,"domain_scores_codex":[0.9985558,0.00004226054,0.0004173117,0.0004675741,0.0002239184,0.0002931802],"domain_scores_gemma":[0.9989069,0.00002065807,0.0002175225,0.0005212137,0.0002052331,0.0001284354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003367518,0.0001239371,0.0001359762,0.00003960991,0.0001603286,0.000003964666,0.00007905115,0.00000111542,0.998409,0.000005603616,0.0008085983,0.0001991824],"study_design_scores_gemma":[0.0004776802,0.00005299768,0.0002959212,0.00005522588,0.0001340669,0.00001755392,0.0002907854,0.000267199,0.996411,0.0001420877,0.001543798,0.0003116757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9658036,0.0004169258,0.03257019,0.0001538609,0.00001966493,0.00008161089,0.0001747118,0.00002641764,0.0007529638],"genre_scores_gemma":[0.9973467,0.00008848838,0.0004055622,0.0002050653,0.000288654,0.00001060404,0.001430453,0.00003807692,0.0001864146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03216463,"threshold_uncertainty_score":0.999973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00831128838712631,"score_gpt":0.2360358706889352,"score_spread":0.2277245823018089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}