{"id":"W2883057518","doi":"10.1534/g3.118.200589","title":"Combinatorial Genetic Control of Rpd3S Through Histone H3K4 and H3K36 Methylation in Budding Yeast","year":2018,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Histone methyltransferase; Genetics; Histone H3; Saccharomyces cerevisiae; Histone; Methyltransferase; Effector; Epigenetics; Histone methylation; Cell biology; Methylation; Yeast; Gene; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002907143,0.0002711009,0.0003400792,0.0001321111,0.0001047859,0.00002866244,0.0003123831,0.000258268,0.00005005901],"category_scores_gemma":[0.00002334872,0.0002821445,0.00008683963,0.0002584228,0.0004433062,0.00000575066,0.0002515283,0.0001179813,0.00001449689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003530987,"about_ca_system_score_gemma":0.0001511141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005642732,"about_ca_topic_score_gemma":0.0001052458,"domain_scores_codex":[0.9979513,0.0001592729,0.0005032079,0.0005757077,0.0003270103,0.0004834933],"domain_scores_gemma":[0.9988754,0.00002721262,0.000151839,0.0005234659,0.000292001,0.0001301313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001998153,0.00008434859,0.02097328,0.00005365441,0.00006238424,0.000002961515,0.0002757634,0.0003617994,0.8480363,0.0001488342,0.0000711376,0.1297296],"study_design_scores_gemma":[0.003450649,0.001728609,0.01558453,0.00002921549,0.00006555793,0.00002687506,0.0001906949,0.001945191,0.8816066,0.001741049,0.09304436,0.0005866277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7851577,0.209691,0.003215029,0.0000512384,0.0004841588,0.0004012775,0.00005648522,0.000009324911,0.0009338207],"genre_scores_gemma":[0.9711191,0.02406528,0.003739572,0.00007396215,0.0007253721,0.00002817232,0.00004216359,0.00004810502,0.0001582751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1859614,"threshold_uncertainty_score":0.999963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01495526428812166,"score_gpt":0.2974051493257492,"score_spread":0.2824498850376275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}