{"id":"W2883057518","doi":"10.1534/g3.118.200589","title":"Combinatorial Genetic Control of Rpd3S Through Histone H3K4 and H3K36 Methylation in Budding Yeast","year":2018,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Histone methyltransferase; Genetics; Histone H3; Saccharomyces cerevisiae; Histone; Methyltransferase; Effector; Epigenetics; Histone methylation; Cell biology; Methylation; Yeast; Gene; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001567537,0.0003616523,0.0002471855,0.000243344,0.0001996471,0.000436484,0.0004049869,0.000237335,0.0009119914],"category_scores_gemma":[0.0001158695,0.00023525,0.0002750674,0.0002250764,0.0003252231,0.00007848098,0.0004329368,0.0005015152,0.0003385943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007238911,"about_ca_system_score_gemma":0.0002849882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001516349,"about_ca_topic_score_gemma":0.002628742,"domain_scores_codex":[0.9998441,0.00002090824,0.00002484933,0.00003067575,0.00005435736,0.00002515987],"domain_scores_gemma":[0.9997911,0.00003565701,0.00005893734,0.00002655339,0.00001857831,0.00006917454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001465113,0.00001422772,0.0001955808,0.00002170309,0.000007082456,0.00005390621,0.00001187839,0.0002271013,0.9984661,0.0001207503,0.00003452205,0.0007006014],"study_design_scores_gemma":[0.00002886645,0.000074808,0.002830591,0.000005269329,0.00001596687,0.0001111882,0.00003132312,0.00226877,0.9930063,0.0000787787,0.001540245,0.000007845917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933114,0.0004326469,0.003752911,0.00007779618,0.00003132922,0.00004036555,0.001091864,0.0002523867,0.001009193],"genre_scores_gemma":[0.9954897,0.0001503171,0.002488145,0.00003265278,0.000002434238,0.00002821581,0.000406155,0.00006164193,0.001340698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001516349,"threshold_uncertainty_score":0.005252302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01495526428812166,"score_gpt":0.2974051493257492,"score_spread":0.2824498850376275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}