{"id":"W2883077238","doi":"10.1111/xen.12432","title":"In vitro characterization of neonatal, juvenile, and adult porcine islet oxygen demand, β‐cell function, and transcriptomes","year":2018,"lang":"en","type":"article","venue":"Xenotransplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institutes of Health; Juvenile Diabetes Research Foundation International","keywords":"Islet; Transcriptome; Biology; Transplantation; Insulin; Xenotransplantation; Andrology; Internal medicine; Endocrinology; In vitro; Cell biology; Gene expression; Gene; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003235509,0.000246856,0.000264469,0.0003160224,0.0001852189,0.0005526198,0.0001815903,0.0002020325,0.0007601673],"category_scores_gemma":[0.000219571,0.0000868597,0.000425008,0.0003131635,0.000198987,0.0002968371,0.0002588281,0.0005135246,0.0003009335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001426267,"about_ca_system_score_gemma":0.0002120624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004790161,"about_ca_topic_score_gemma":0.0006187812,"domain_scores_codex":[0.9998581,0.00001022888,0.00001426521,0.0000466304,0.00004729025,0.00002339992],"domain_scores_gemma":[0.9997566,0.00005863873,0.00005917094,0.0000275023,0.00005234032,0.00004577882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001020117,0.00002599418,0.004087382,0.00008834973,0.0000146139,0.0001042749,0.00007969107,0.0001051342,0.992574,0.00004323582,0.0000616617,0.002713633],"study_design_scores_gemma":[0.00002275957,0.001128213,0.3125781,0.00009483364,0.0002148797,0.001327305,0.0006655816,0.002067542,0.669296,0.0002677873,0.01229722,0.00003983481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741541,0.00442342,0.0135447,0.00008111077,0.00006180482,0.00008515037,0.003025719,0.00007843418,0.004545565],"genre_scores_gemma":[0.9683059,0.004087982,0.01190677,0.0003021721,0.00006006753,0.0003426951,0.01175567,0.00009794862,0.003140922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007601673,"threshold_uncertainty_score":0.002543032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006067253994995437,"score_gpt":0.214819735549286,"score_spread":0.2087524815542905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}