{"id":"W2883099048","doi":"10.1177/1352458518791683","title":"Multiple sclerosis disease progression: Contributions from a hypoxia–inflammation cycle","year":2018,"lang":"en","type":"article","venue":"Multiple Sclerosis Journal","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Multiple sclerosis; Hypoxia (environmental); Medicine; Inflammation; Disease; Neuroscience; Pathology; Internal medicine; Psychology; Immunology; Chemistry; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000706534,0.0003264233,0.0003642454,0.0002377757,0.001805572,0.0002183564,0.0004101999,0.0003212042,0.00237421],"category_scores_gemma":[0.001645328,0.0002885342,0.0002996695,0.0002754371,0.0004283819,0.0007471322,0.0001471341,0.0005753348,0.002455287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001796899,"about_ca_system_score_gemma":0.0001963175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009987587,"about_ca_topic_score_gemma":0.00005033471,"domain_scores_codex":[0.9972642,0.0006394513,0.0008246811,0.0004005768,0.0001795756,0.000691489],"domain_scores_gemma":[0.997754,0.0004635187,0.0005216544,0.0004889126,0.0005932451,0.0001786164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001723813,0.0001804532,0.01054684,0.000005603617,0.0002103784,0.000005612631,0.0005750614,0.00002982523,0.9277457,0.00004470908,0.004906712,0.0540253],"study_design_scores_gemma":[0.006661443,0.0002391909,0.4262163,0.0005265393,0.0001439681,0.00003464954,0.0002126638,0.001193887,0.5350175,0.0002650283,0.02905624,0.0004325326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883346,0.002576674,0.004412104,0.001712126,0.001933819,0.0004471127,0.0002123462,0.0001831565,0.0001880643],"genre_scores_gemma":[0.9968848,0.0003886865,0.0008327712,0.0001353098,0.0009803633,0.00008027057,0.000408476,0.00003976164,0.0002496006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4156695,"threshold_uncertainty_score":0.9999567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03506694740630822,"score_gpt":0.2535463237380111,"score_spread":0.2184793763317028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}