{"id":"W2883200523","doi":"10.3390/magnetochemistry4030032","title":"Structure Confirmation and Evaluation of a Nonsteroidal Inhibitor of 17β-Hydroxysteroid Dehydrogenase Type 10","year":2018,"lang":"en","type":"article","venue":"Magnetochemistry","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Mitacs","keywords":"Benzothiazole; Chemistry; HEK 293 cells; Dehydrogenase; Phosphonate; Enzyme; Steroid; Transfection; Stereochemistry; Hydroxysteroid dehydrogenase; Biochemistry; Receptor; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003386007,0.0005472012,0.0005370083,0.0004161355,0.0003359748,0.0003226767,0.0006361397,0.00045596,0.002194887],"category_scores_gemma":[0.0003214418,0.0002075428,0.0005109096,0.0002546709,0.0002669369,0.0002356331,0.0001576306,0.0006226677,0.0005462054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003741102,"about_ca_system_score_gemma":0.0004528029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001537811,"about_ca_topic_score_gemma":0.003043315,"domain_scores_codex":[0.9998357,0.00003913851,0.00001114165,0.00002546908,0.00003411115,0.00005443881],"domain_scores_gemma":[0.9998516,0.00002522909,0.00001897731,0.00001647858,0.00004371244,0.00004395788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008216602,0.0006516438,0.0002682139,0.0002434075,0.00004978132,0.0004601524,0.0001039026,0.0006857752,0.9900247,0.0002548,0.0003357457,0.006100187],"study_design_scores_gemma":[0.0009213511,0.01440868,0.004048937,0.00003903345,0.0001985642,0.001053014,0.00008475686,0.002098018,0.9634008,0.0001146321,0.01359832,0.00003389293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802492,0.008146585,0.004457637,0.0004329573,0.0001474993,0.0004319911,0.001355043,0.0001218155,0.004657233],"genre_scores_gemma":[0.9817504,0.006244024,0.004539365,0.0002285984,0.0000579463,0.000129831,0.002536431,0.00002590575,0.004487646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002194887,"threshold_uncertainty_score":0.007342637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02380755789829906,"score_gpt":0.2941265788233036,"score_spread":0.2703190209250045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}