{"id":"W2883211446","doi":"10.1101/370387","title":"The phospholamban pentamer interacts with the sarcoplasmic reticulum calcium pump SERCA","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Heart and Stroke Foundation of Canada","keywords":"Phospholamban; Pentamer; SERCA; Endoplasmic reticulum; Chemistry; Biophysics; Contractility; Biochemistry; Biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001276228,0.0003155494,0.0005489719,0.0002650561,0.000446832,0.0007314898,0.0003842544,0.0004674913,0.001733257],"category_scores_gemma":[0.0002801904,0.0003577162,0.0003765411,0.0001800005,0.0004368844,0.0004484915,0.0003784268,0.0008321893,0.0003713577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006768607,"about_ca_system_score_gemma":0.0002602723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005646957,"about_ca_topic_score_gemma":0.0005311916,"domain_scores_codex":[0.9997818,0.00002618104,0.0000152322,0.00005483191,0.00008590567,0.00003601352],"domain_scores_gemma":[0.9996879,0.00005934041,0.00008944289,0.00002977277,0.00002869578,0.0001048385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002749168,0.0001383492,0.001675571,0.00007725701,0.00004002709,0.0005029893,0.00007919924,0.001277796,0.9942806,0.0005622055,0.0001749025,0.0009162623],"study_design_scores_gemma":[0.0001738713,0.0005098571,0.02807285,0.00004274876,0.0001029035,0.001740531,0.0003957761,0.03676291,0.9283791,0.0007647179,0.002989033,0.0000656277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963755,0.0004480105,0.001797812,0.0001271674,0.00003631432,0.00001027774,0.00004456542,0.00008329903,0.001077041],"genre_scores_gemma":[0.997707,0.000124863,0.001326695,0.00007999668,0.000008624873,0.00001086341,0.0001307412,0.00001627209,0.0005948442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001733257,"threshold_uncertainty_score":0.00579828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01020023188045773,"score_gpt":0.2192952265116357,"score_spread":0.2090949946311779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}