{"id":"W2883218478","doi":"10.1016/j.transci.2018.07.011","title":"Treatment and prevention of bleeding in congenital hemophilia A patients with inhibitors","year":2018,"lang":"en","type":"review","venue":"Transfusion and Apheresis Science","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"","keywords":"Medicine; PROTHROMBIN COMPLEX; Prothrombin complex concentrate; Tissue factor pathway inhibitor; Recombinant factor VIIa; Antithrombin; Factor IX; Coagulopathy; Coagulation; Off-label use; Surgery; Intensive care medicine; Internal medicine; Heparin; Warfarin; Tissue factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006963239,0.0006049653,0.002093453,0.001755125,0.000191071,0.0009159623,0.001036076,0.001126849,0.002449035],"category_scores_gemma":[0.002008082,0.0002744879,0.001245475,0.001290616,0.0003195702,0.0006491177,0.0003462924,0.001334722,0.0003748472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003255929,"about_ca_system_score_gemma":0.0007219563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001457357,"about_ca_topic_score_gemma":0.002243368,"domain_scores_codex":[0.999648,0.00009032116,0.00008702551,0.00005123466,0.0001008175,0.00002269826],"domain_scores_gemma":[0.999308,0.0004727361,0.0001307598,0.000009251835,0.0000595695,0.00001965008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002783039,0.0001350763,0.0006393721,0.07759091,0.001003286,0.000246353,0.00006448493,0.0002804779,0.0005025121,0.001284375,0.01262549,0.9053493],"study_design_scores_gemma":[0.0008066146,0.001007354,0.01052027,0.1287072,0.01043921,0.008407927,0.0002602082,0.0005062586,0.001176919,0.003352488,0.8346894,0.0001261278],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008031463,0.9997035,0.00001915195,0.0000509589,0.00003076636,0.000001872934,0.00000618234,7.976161e-7,0.0001064512],"genre_scores_gemma":[0.00111824,0.9985093,0.00009033761,0.0001095706,0.00008967016,0.000004016534,0.00001603013,4.151175e-7,0.00006226714],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002449035,"threshold_uncertainty_score":0.008192837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04304539977153668,"score_gpt":0.3400625243298652,"score_spread":0.2970171245583285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}