{"id":"W2883218478","doi":"10.1016/j.transci.2018.07.011","title":"Treatment and prevention of bleeding in congenital hemophilia A patients with inhibitors","year":2018,"lang":"en","type":"review","venue":"Transfusion and Apheresis Science","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"","keywords":"Medicine; PROTHROMBIN COMPLEX; Prothrombin complex concentrate; Tissue factor pathway inhibitor; Recombinant factor VIIa; Antithrombin; Factor IX; Coagulopathy; Coagulation; Off-label use; Surgery; Intensive care medicine; Internal medicine; Heparin; Warfarin; Tissue factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002083302,0.0002253734,0.0007188583,0.0003575981,0.0001114543,0.00002365374,0.00006544673,0.0001050826,0.00004449552],"category_scores_gemma":[0.00001790768,0.0001235706,0.00008663027,0.0007035977,0.0007377518,0.0001080729,0.00002824803,0.00009519012,0.000002287808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009236585,"about_ca_system_score_gemma":0.0003246607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006611857,"about_ca_topic_score_gemma":0.00007140604,"domain_scores_codex":[0.9985836,0.00003963153,0.0003082161,0.0004564594,0.0003730924,0.0002390154],"domain_scores_gemma":[0.9994686,0.00004950229,0.00007449604,0.0001476033,0.00008622801,0.0001735196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001180828,0.0003775604,0.01086528,0.002954408,0.00004809605,0.00001098577,0.0002913,8.72144e-9,0.00006675267,0.00001305631,0.000004721563,0.9852498],"study_design_scores_gemma":[0.0835958,0.08078896,0.1525485,0.2899838,0.01354418,0.000718862,0.002482565,0.0001900393,0.005991091,0.0003378679,0.3646029,0.005215384],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.563763,0.4344009,9.501506e-7,0.00002223218,0.00003671725,0.001228683,0.000008498296,0.000008328539,0.0005307666],"genre_scores_gemma":[0.04757313,0.9517288,0.0001594882,0.000001704405,0.00002553207,0.00003176893,0.00001084532,0.00001337501,0.0004553852],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.9800344,"threshold_uncertainty_score":0.5039064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04304539977153668,"score_gpt":0.3400625243298652,"score_spread":0.2970171245583285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}