{"id":"W2883254892","doi":"10.1039/c8np00046h","title":"Polysaccharides from<i>Burkholderia</i>species as targets for vaccine development, immunomodulation and chemical synthesis","year":2018,"lang":"en","type":"review","venue":"Natural Product Reports","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec; Armand Frappier Museum","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Réseau Québécois de Recherche sur les Médicaments","keywords":"Burkholderia pseudomallei; Melioidosis; Microbiology; Burkholderia; Biofilm; Biology; Burkholderia cepacia complex; Polysaccharide; Virulence; Glycoconjugate; Bacteria; Antibiotics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003072075,0.0007862044,0.0006353281,0.001607875,0.0002796396,0.0009026505,0.0004276956,0.000592967,0.007377982],"category_scores_gemma":[0.0003744374,0.0002205899,0.0003239735,0.001825856,0.0002770905,0.001217004,0.0007178927,0.001072966,0.004952105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004642119,"about_ca_system_score_gemma":0.000716947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005172887,"about_ca_topic_score_gemma":0.0007950015,"domain_scores_codex":[0.999837,0.00001505689,0.0000146297,0.0000268739,0.00007507889,0.00003120625],"domain_scores_gemma":[0.9998813,0.00002783744,0.00002465934,0.000007962594,0.00003589945,0.00002238756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007964206,0.00009649224,0.0001849033,0.02184653,0.00006381228,0.0002170756,0.000103427,0.0006831348,0.03184227,0.01040205,0.03974064,0.8947399],"study_design_scores_gemma":[0.000004833507,0.0000751745,0.0003334077,0.001095855,0.0000250018,0.0003424243,0.00002921822,0.00007770798,0.004115308,0.0009391205,0.9929512,0.0000107483],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001300017,0.9850759,0.0006698368,0.0003510679,0.0009076951,0.00002358956,0.000124582,0.00003721295,0.01151008],"genre_scores_gemma":[0.005093492,0.9866995,0.0006664452,0.0002284085,0.0002917296,0.00002293225,0.000183802,0.000008687728,0.006805021],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007377982,"threshold_uncertainty_score":0.02468181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02833164953777144,"score_gpt":0.2779434262434043,"score_spread":0.2496117767056329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}