{"id":"W2883254892","doi":"10.1039/c8np00046h","title":"Polysaccharides from<i>Burkholderia</i>species as targets for vaccine development, immunomodulation and chemical synthesis","year":2018,"lang":"en","type":"review","venue":"Natural Product Reports","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec; Armand Frappier Museum","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Réseau Québécois de Recherche sur les Médicaments","keywords":"Burkholderia pseudomallei; Melioidosis; Microbiology; Burkholderia; Biofilm; Biology; Burkholderia cepacia complex; Polysaccharide; Virulence; Glycoconjugate; Bacteria; Antibiotics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004092595,0.0009130348,0.002018747,0.00009914511,0.0002559199,0.0001860347,0.0003229226,0.0006401618,0.0008036307],"category_scores_gemma":[0.002988511,0.000752828,0.0005197327,0.0001866469,0.0001051569,0.0002030333,0.0002384798,0.0005084414,0.00001497084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002833606,"about_ca_system_score_gemma":0.0003908774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000427785,"about_ca_topic_score_gemma":0.000003009804,"domain_scores_codex":[0.9957505,0.00002788007,0.001546295,0.001741568,0.0003963577,0.0005374279],"domain_scores_gemma":[0.9966373,0.0005107923,0.001288919,0.001145535,0.0002607045,0.0001567623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007928253,0.0001008844,0.00002613051,0.01741714,0.001162647,0.0001474586,0.0001402089,4.414152e-8,0.26226,0.000003771988,0.003201082,0.7154613],"study_design_scores_gemma":[0.00005611429,0.000002479122,0.000004090813,0.002786543,0.0005754207,0.0003887096,0.00000829365,9.220484e-7,0.4568761,0.00008654079,0.5386311,0.0005836166],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01985773,0.9778641,0.000001731541,0.00005377932,0.0006571071,0.0005174127,0.00009131502,0.0001838903,0.0007729644],"genre_scores_gemma":[0.03519205,0.9505796,0.001746747,0.00001795599,0.003745892,0.0006801758,0.002292113,0.0002073293,0.005538121],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7148777,"threshold_uncertainty_score":0.9994923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02833164953777144,"score_gpt":0.2779434262434043,"score_spread":0.2496117767056329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}