{"id":"W2883387203","doi":"10.1152/ajplung.00286.2018","title":"Human pulmonary endothelial cell permeability after exposure to LPS-stimulated leukocyte supernatants derived from patients with early sepsis","year":2018,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Heart, Lung, and Blood Institute","keywords":"Sepsis; Lipopolysaccharide; Vascular permeability; Endothelial stem cell; ARDS; Immunology; Endothelial activation; Inflammation; Permeability (electromagnetism); Biology; Medicine; Lung; In vitro; Pathology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002055191,0.0001629136,0.0002434252,0.0002098879,0.00009868487,0.0003205145,0.00008499344,0.0001934206,0.0007504799],"category_scores_gemma":[0.0003953731,0.00009288436,0.000108017,0.0001926962,0.0001286273,0.0001653427,0.0001793871,0.0004016228,0.0001475617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009899278,"about_ca_system_score_gemma":0.00006368323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001867247,"about_ca_topic_score_gemma":0.0001697625,"domain_scores_codex":[0.9997213,0.00008646521,0.00002500726,0.00005513513,0.00007074159,0.00004120123],"domain_scores_gemma":[0.9998294,0.00004396721,0.00005550381,0.00001709991,0.00002648556,0.00002753642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009735271,0.00007767481,0.01797698,0.00005861463,0.00002738413,0.0003517633,0.0001815161,0.0001107347,0.9762649,0.00003483476,0.00005913229,0.003882946],"study_design_scores_gemma":[0.00003967071,0.002743632,0.3895041,0.00001933326,0.0001003508,0.002932826,0.0005468114,0.0020659,0.6007187,0.0001018017,0.001207327,0.00001953651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984685,0.0004533171,0.000747302,0.00002622204,0.000004115589,0.000007853673,0.0001144191,0.000008477538,0.0001696991],"genre_scores_gemma":[0.9992191,0.0001363895,0.0002806588,0.00002856202,0.000004296032,0.00001059393,0.0001895477,0.000001334319,0.0001296327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007504799,"threshold_uncertainty_score":0.002510607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00386769033894,"score_gpt":0.2024396628761291,"score_spread":0.1985719725371891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}