{"id":"W2883461409","doi":"10.1097/01.cot.0000544200.02646.06","title":"Genome-Wide Sequencing Detects Early Stage Lung Cancer From Blood Samples","year":2018,"lang":"en","type":"article","venue":"Oncology Times","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Lung cancer; Indel; Cancer; Genome; Stage (stratigraphy); DNA sequencing; Cell-free fetal DNA; Biology; Oncology; Computational biology; DNA; Gene; Internal medicine; Medicine; Single-nucleotide polymorphism; Genetics; Genotype","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001037972,0.0001742801,0.0002108163,0.00003839715,0.0001362846,0.00003111959,0.0002320115,0.0002423531,0.0006145072],"category_scores_gemma":[0.0001435778,0.0001785515,0.00007256247,0.00006197746,0.0001902869,0.000003947604,0.0001810909,0.0001007389,0.00003872393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001110471,"about_ca_system_score_gemma":0.000557299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001885769,"about_ca_topic_score_gemma":0.002951376,"domain_scores_codex":[0.9989049,0.00004820773,0.0001991708,0.0004264723,0.00007756682,0.0003436789],"domain_scores_gemma":[0.9992117,0.00009813298,0.0001159582,0.0003476414,0.0001112842,0.0001153399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001207842,0.00005497145,0.0667843,0.00001122561,0.0003258958,0.00003018825,0.0003695526,0.00008122972,0.9246033,0.00006414129,0.005363754,0.00219065],"study_design_scores_gemma":[0.001287573,0.001096349,0.05281866,0.00001922924,0.000211912,0.000006789286,0.0001189618,0.00009365332,0.5638654,0.0002236444,0.3798123,0.0004455195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886985,0.003507938,0.0006190054,0.0001842495,0.0004969001,0.0001647183,0.0002663429,0.00002080019,0.006041479],"genre_scores_gemma":[0.9909939,0.001059322,0.002425658,0.001188739,0.00146981,0.00005175657,0.0001199132,0.00003725034,0.002653653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3744485,"threshold_uncertainty_score":0.7281117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01361494847394373,"score_gpt":0.2735475298504267,"score_spread":0.259932581376483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}