{"id":"W2883638492","doi":"10.3390/diseases6030064","title":"Host Protein BAG3 is a Negative Regulator of Lassa VLP Egress","year":2018,"lang":"en","type":"article","venue":"Diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; University of Pennsylvania; National Institutes of Health; Cancer Prevention and Research Institute of Texas","keywords":"Lassa virus; BAG3; WW domain; Biology; VP40; Cell biology; Capsid; TSG101; Virology; Virus; Chaperone (clinical); Viral replication; Autophagy; Genetics; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001091821,0.0005036948,0.0002280885,0.0003187614,0.0004102181,0.0003590052,0.0001500885,0.0002266724,0.00276176],"category_scores_gemma":[0.0001253652,0.0001001986,0.0003012533,0.0002715411,0.0001558732,0.0001902527,0.0003950582,0.000397094,0.001051871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003610806,"about_ca_system_score_gemma":0.0001694668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003822928,"about_ca_topic_score_gemma":0.0004283254,"domain_scores_codex":[0.9998354,0.00002345431,0.0000100479,0.00003414034,0.00005510304,0.00004196618],"domain_scores_gemma":[0.9998409,0.00001269207,0.00007366628,0.000007404539,0.00001897649,0.00004637247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003559165,0.00004605019,0.007706702,0.0001603493,0.00004602964,0.0009473762,0.00003573572,0.0001585526,0.9770458,0.0004529042,0.001856962,0.01118778],"study_design_scores_gemma":[0.00008247157,0.0006702056,0.2046338,0.00005580109,0.0001782333,0.01747383,0.0002655361,0.00583505,0.6938819,0.001437207,0.07541604,0.00006993907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9599528,0.01398326,0.01128564,0.0005225636,0.0002539473,0.00006622905,0.003895886,0.001500472,0.008539184],"genre_scores_gemma":[0.9868231,0.001668384,0.002090534,0.0002457143,0.00003928119,0.00004508819,0.003767125,0.0000623258,0.00525844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00276176,"threshold_uncertainty_score":0.009238958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02011340826286178,"score_gpt":0.3352260772885871,"score_spread":0.3151126690257253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}