{"id":"W2883638492","doi":"10.3390/diseases6030064","title":"Host Protein BAG3 is a Negative Regulator of Lassa VLP Egress","year":2018,"lang":"en","type":"article","venue":"Diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; University of Pennsylvania; National Institutes of Health; Cancer Prevention and Research Institute of Texas","keywords":"Lassa virus; BAG3; WW domain; Biology; VP40; Cell biology; Capsid; TSG101; Virology; Virus; Chaperone (clinical); Viral replication; Autophagy; Genetics; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00004401611,0.00008276106,0.0001703106,0.00009207882,0.00007500799,0.00001277353,0.000052729,0.00003932096,0.001418397],"category_scores_gemma":[0.0001999738,0.00006164306,0.00009493907,0.0002473916,0.0002902501,0.00006581332,0.00004604497,0.00006489288,0.0001130936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002792215,"about_ca_system_score_gemma":0.0001267863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001985904,"about_ca_topic_score_gemma":0.00001342678,"domain_scores_codex":[0.9992587,0.00003243764,0.0001282196,0.0001615586,0.0002488879,0.0001701736],"domain_scores_gemma":[0.9992232,0.00002772695,0.00004313658,0.0002314095,0.0003023617,0.0001722219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005378376,0.005038662,0.4084658,0.001930095,0.001166413,0.000214918,0.002601949,8.380363e-7,0.351702,0.007381262,0.148138,0.06798173],"study_design_scores_gemma":[0.001800984,0.001505481,0.5758929,0.0004760691,0.0001278636,0.00000902715,0.0003022903,0.0002921998,0.4002472,0.0004763369,0.01869525,0.0001743183],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923033,0.0002290271,0.00002745895,0.0009626997,0.00004465811,0.0004671216,0.0001461612,0.00003973642,0.005779889],"genre_scores_gemma":[0.994693,0.00000943434,0.00009997412,0.0001877921,0.0002490316,0.0000481475,0.000009530328,0.0000130482,0.004690012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1674272,"threshold_uncertainty_score":0.9994944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02011340826286178,"score_gpt":0.3352260772885871,"score_spread":0.3151126690257253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}