{"id":"W2883643014","doi":"10.7554/elife.37963","title":"SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion","year":2018,"lang":"en","type":"article","venue":"eLife","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Cystic Fibrosis Canada","keywords":"Amino acid transporter; Transporter; Arginine; Mutant; Secretion; Chemistry; Mutation; Amino acid; Biochemistry; Biology; Cystic fibrosis; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002255597,0.0004000026,0.0003339183,0.0003376229,0.0001881616,0.0002656831,0.0002269142,0.0005248432,0.0009881078],"category_scores_gemma":[0.0002863742,0.0001541303,0.0002791204,0.0001583678,0.0005356988,0.0001636116,0.0002835414,0.0003729161,0.0002284135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000215081,"about_ca_system_score_gemma":0.0002800764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000628164,"about_ca_topic_score_gemma":0.001209263,"domain_scores_codex":[0.9997486,0.00005960009,0.00002501047,0.00005728756,0.0000676987,0.00004168653],"domain_scores_gemma":[0.9998413,0.00002631236,0.00005964997,0.00001663085,0.00001769,0.00003841809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001148286,0.00001319814,0.001409559,0.00002424869,0.000008419464,0.0001950031,0.00001236469,0.0000500178,0.9961934,0.00007738343,0.00004106962,0.001860467],"study_design_scores_gemma":[0.00004170145,0.000487388,0.04689842,0.00001439677,0.0000590481,0.003757633,0.0000990017,0.001246718,0.942471,0.000312517,0.004599066,0.00001310421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946641,0.001112981,0.002865975,0.000230002,0.00004643942,0.00001789479,0.0002715933,0.00007734359,0.0007136688],"genre_scores_gemma":[0.9935406,0.0009160712,0.003491875,0.00008365572,0.00001400683,0.00001375291,0.0002107365,0.00002184634,0.001707574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009881078,"threshold_uncertainty_score":0.003305495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02320205521667573,"score_gpt":0.3087086976034264,"score_spread":0.2855066423867507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}