{"id":"W2883731185","doi":"10.20944/preprints201807.0520.v1","title":"The Response of <em>Cupriavidus Metallidurans</em> CH34 to Cadmium Involves a Decrease in Intracellular Levels of C-Di-GMP Probably Mediated by a Novel Metal Regulated Phosphodiesterase That Inhibits the Biofilm Lifestyle","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Chromium effects and bioremediation","field":"Environmental Science","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Biofilm; Cadmium; Phosphodiesterase; Biology; Microbiology; Chemistry; Biochemistry; Bacteria; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.008056993,0.0008834837,0.001127354,0.0002328638,0.0002528802,0.00009397122,0.001917886,0.0006825511,0.0007299847],"category_scores_gemma":[0.00472627,0.0005904568,0.000407411,0.001037315,0.001050363,0.00029305,0.003446528,0.0008436624,0.000261833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000567021,"about_ca_system_score_gemma":0.0003842538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001303711,"about_ca_topic_score_gemma":0.002279215,"domain_scores_codex":[0.9928198,0.001355064,0.001655206,0.001621522,0.001678291,0.000870126],"domain_scores_gemma":[0.9943256,0.001251472,0.001417807,0.002325013,0.0001841309,0.0004959749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002104216,0.0006780972,0.03494245,0.0001251328,0.0002682462,0.0000174864,0.005161098,0.0006367851,0.9554801,0.00001541214,0.000181916,0.0003890308],"study_design_scores_gemma":[0.00122842,0.0001358369,0.2849679,0.0003053124,0.0001936198,0.00001098138,0.000179258,0.000967797,0.710022,0.0001199815,0.001319528,0.000549413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931725,0.0005831475,0.0000997287,0.001240367,0.000493837,0.003708029,0.0005096032,0.00009007321,0.0001027286],"genre_scores_gemma":[0.9979928,0.0002207874,0.0003798498,0.0001837918,0.00008047627,0.0004482564,0.0001502689,0.00008904445,0.000454732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2500255,"threshold_uncertainty_score":0.9996547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04365901920096218,"score_gpt":0.2706720453086872,"score_spread":0.227013026107725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}