{"id":"W2883731185","doi":"10.20944/preprints201807.0520.v1","title":"The Response of <em>Cupriavidus Metallidurans</em> CH34 to Cadmium Involves a Decrease in Intracellular Levels of C-Di-GMP Probably Mediated by a Novel Metal Regulated Phosphodiesterase That Inhibits the Biofilm Lifestyle","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Chromium effects and bioremediation","field":"Environmental Science","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Biofilm; Cadmium; Phosphodiesterase; Biology; Microbiology; Chemistry; Biochemistry; Bacteria; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001136965,0.0006587505,0.0003338171,0.0002396323,0.0001411002,0.000208027,0.0003647446,0.0003519023,0.001361999],"category_scores_gemma":[0.0001946642,0.0001742478,0.0002828446,0.0002119488,0.0001845803,0.0001468884,0.0003529379,0.0004613325,0.0003067319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000299507,"about_ca_system_score_gemma":0.0001550042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002665346,"about_ca_topic_score_gemma":0.002459197,"domain_scores_codex":[0.9998245,0.00001786633,0.00001960587,0.00004671562,0.00005780808,0.00003362176],"domain_scores_gemma":[0.9998528,0.00002116408,0.00005138678,0.00002116772,0.00002568995,0.00002770798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003395954,0.00001043683,0.0001578028,0.00001786076,0.000002422836,0.00002758077,0.000005878124,0.00002033355,0.9992999,0.00001422667,0.00002152463,0.0003880602],"study_design_scores_gemma":[0.00001337458,0.0004263905,0.02275272,0.000005763591,0.00002056239,0.0003361226,0.00007505962,0.0006942857,0.973864,0.00004119196,0.00175608,0.00001448512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961286,0.0002167502,0.00159448,0.0001157965,0.00001851936,0.00003437121,0.00112273,0.00009097746,0.0006777627],"genre_scores_gemma":[0.9892458,0.0001827569,0.004014243,0.00007909136,0.000008585862,0.0000570233,0.00236553,0.00005054428,0.003996354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002665346,"threshold_uncertainty_score":0.005299628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04365901920096218,"score_gpt":0.2706720453086872,"score_spread":0.227013026107725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}