{"id":"W2883787065","doi":"","title":"Genomics and Biomarker Research in Drug Development: Overrated, or a Revolution to Come?","year":2017,"lang":"en","type":"article","venue":"UBC Faculty of Medicine medical journal","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Pharmacogenomics; Personalized medicine; Drug development; Engineering ethics; Field (mathematics); Biomarker; Precision medicine; Genomics; Data science; Medicine; Computer science; Drug; Bioinformatics; Biology; Engineering; Pharmacology; Pathology; Genome","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1150198,0.001775494,0.004925298,0.00280456,0.004561034,0.01520983,0.004841682,0.02100136,0.01079308],"category_scores_gemma":[0.09030463,0.001028254,0.001795699,0.004213725,0.04023104,0.05452301,0.01119524,0.02937177,0.004004833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007698597,"about_ca_system_score_gemma":0.0143713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006357067,"about_ca_topic_score_gemma":0.005107995,"domain_scores_codex":[0.9570944,0.02330892,0.003082214,0.004466746,0.009541643,0.002506043],"domain_scores_gemma":[0.8706588,0.08538724,0.004523114,0.01031245,0.02168959,0.007428823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008230986,0.0003046165,0.002821952,0.004683325,0.0003889968,0.0004826523,0.00178347,0.001109899,0.0009435369,0.4038761,0.1764076,0.4063747],"study_design_scores_gemma":[0.0002971627,0.000560796,0.00261367,0.007398108,0.0002347078,0.001016153,0.004169023,0.00161817,0.0005148497,0.5574034,0.4238853,0.0002885493],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001156519,0.2223918,0.004437747,0.7591122,0.009437388,0.00002037505,0.00006464299,0.0001001319,0.003279173],"genre_scores_gemma":[0.08738618,0.3309373,0.02195104,0.5105414,0.04321602,0.0001876326,0.0001461237,0.0002267483,0.005407681],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1150198,"threshold_uncertainty_score":0.6082901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3611985502018332,"score_gpt":0.5514500067521504,"score_spread":0.1902514565503172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}