{"id":"W2883866956","doi":"10.1158/2326-6066.cir-18-0037","title":"Response to Immune Checkpoint Inhibition in Two Patients with Alveolar Soft-Part Sarcoma","year":2018,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital; Hospital for Sick Children; Princess Margaret Cancer Centre","funders":"MedImmune","keywords":"Alveolar soft part sarcoma; Sarcoma; Medicine; Soft tissue sarcoma; Immunotherapy; Immune checkpoint; Immune system; Cancer research; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002632762,0.0005462476,0.0006105958,0.0004499161,0.0006601825,0.0006084971,0.0003119448,0.001114691,0.000880032],"category_scores_gemma":[0.001118043,0.0002161365,0.0004721495,0.0002443805,0.0004882691,0.0002921406,0.0004289951,0.0009991585,0.0002340142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000754552,"about_ca_system_score_gemma":0.000312688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006140404,"about_ca_topic_score_gemma":0.0007174993,"domain_scores_codex":[0.9997354,0.00004244618,0.00003323851,0.00006265091,0.00003753446,0.0000886503],"domain_scores_gemma":[0.9994527,0.0001433389,0.00006463229,0.00003469109,0.000036862,0.000267909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.004802364,0.001794914,0.3245948,0.0001458543,0.0001721989,0.5898018,0.001266921,0.001489473,0.03277174,0.001046593,0.001525547,0.04058778],"study_design_scores_gemma":[0.0008103005,0.008842554,0.2223774,0.00003854356,0.0001507775,0.7508059,0.0006166931,0.004556547,0.007381216,0.0006997301,0.003656677,0.00006368785],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996206,0.0003220294,0.0003770298,0.0004963796,0.00003021531,0.00005933342,0.00007808229,0.00002270316,0.002408217],"genre_scores_gemma":[0.9992981,0.0000734911,0.0001480005,0.000146599,0.00002754342,0.000009847377,0.00006621006,0.000002917666,0.0002272929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001114691,"threshold_uncertainty_score":0.005474687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0473021969530328,"score_gpt":0.3882202883024161,"score_spread":0.3409180913493833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}