{"id":"W2883971260","doi":"10.1097/tp.0000000000002373","title":"Deep Profiling of the CD8+ T-cell Compartment Identifies Activated Cell Subsets and Multifunctional Responses Associated With Control of Cytomegalovirus Viremia","year":2018,"lang":"en","type":"article","venue":"Transplantation","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Viremia; Human cytomegalovirus; CD8; Immunology; Biology; Cytotoxic T cell; T cell; Virology; IL-2 receptor; Peripheral blood mononuclear cell; CD28; Immune system; Virus; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000859218,0.0001551993,0.0001702096,0.0002049412,0.00009990125,0.0003009459,0.00009902366,0.000156644,0.0006567358],"category_scores_gemma":[0.0001395186,0.0000753427,0.0001047633,0.0001272132,0.000111258,0.0001501075,0.0002016505,0.000233622,0.0001498591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001201368,"about_ca_system_score_gemma":0.00005514405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002066178,"about_ca_topic_score_gemma":0.0003390743,"domain_scores_codex":[0.9999452,0.000005637313,0.000002868552,0.00001772323,0.0000100191,0.00001856298],"domain_scores_gemma":[0.9999301,0.00001349966,0.00001894939,0.000007935972,0.00001312789,0.0000163706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001825697,0.00001471946,0.008733946,0.00002340979,0.000007028859,0.00002961816,0.0000679739,0.0001792391,0.9864843,0.00003369284,0.00003387155,0.004209742],"study_design_scores_gemma":[0.00002706325,0.001071729,0.3543921,0.00002635691,0.0001180672,0.001041956,0.0004229257,0.01344527,0.6261532,0.0005021785,0.002782105,0.00001698725],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997173,0.0001482721,0.00217459,0.000008747309,0.000001489419,0.000007322233,0.0001599061,0.00002644751,0.0003002097],"genre_scores_gemma":[0.9974048,0.0001005043,0.001745122,0.00002468895,0.000003535003,0.00002008143,0.0003242117,0.000008864109,0.0003682113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006567358,"threshold_uncertainty_score":0.002196968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02189506564462885,"score_gpt":0.2797405447696845,"score_spread":0.2578454791250556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}