{"id":"W2883971260","doi":"10.1097/tp.0000000000002373","title":"Deep Profiling of the CD8+ T-cell Compartment Identifies Activated Cell Subsets and Multifunctional Responses Associated With Control of Cytomegalovirus Viremia","year":2018,"lang":"en","type":"article","venue":"Transplantation","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Viremia; Human cytomegalovirus; CD8; Immunology; Biology; Cytotoxic T cell; T cell; Virology; IL-2 receptor; Peripheral blood mononuclear cell; CD28; Immune system; Virus; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003154182,0.0001259467,0.0002699897,0.0001234862,0.0001220226,0.0000133012,0.00006535318,0.00007949237,0.00006522405],"category_scores_gemma":[0.00003296195,0.00008396355,0.00005481887,0.0002469486,0.0003074418,0.00009135129,0.000007264712,0.0001497022,0.000005670241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005140597,"about_ca_system_score_gemma":0.0001367324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001372903,"about_ca_topic_score_gemma":0.000297395,"domain_scores_codex":[0.9987268,0.000141276,0.0003068715,0.0001864493,0.0004619935,0.0001765875],"domain_scores_gemma":[0.9989849,0.0003026824,0.000186249,0.0001476574,0.0003181068,0.00006044442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009471606,0.0002526137,0.08156729,0.0002822499,0.0001101846,0.000006568037,0.0009791604,0.00005400534,0.9071021,0.00001654855,0.0000142244,0.0001434512],"study_design_scores_gemma":[0.005054918,0.0003477368,0.2708842,0.0001400654,0.0001931339,0.000009080613,0.0001170338,0.001529231,0.7216349,0.00000718556,0.00001572061,0.00006677536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976445,0.0001089587,0.000889079,0.00006152574,0.00004744968,0.0006423193,0.0001387716,0.00001998255,0.0004474496],"genre_scores_gemma":[0.9994124,0.00006723769,0.0001386815,0.00004015853,0.00002662672,0.00001814181,0.00007347122,0.00001609558,0.0002072353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.189317,"threshold_uncertainty_score":0.3423934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02189506564462885,"score_gpt":0.2797405447696845,"score_spread":0.2578454791250556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}