{"id":"W2884008478","doi":"10.1002/anie.201805673","title":"Genome‐Based Identification of a Plant‐Associated Marine Bacterium as a Rich Natural Product Source","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"H2020 European Research Council; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Alexander von Humboldt-Stiftung","keywords":"Biology; Natural product; Genome; Gene cluster; Gene; Bacteria; Polyketide synthase; Whole genome sequencing; Shewanella; Polyketide; Horizontal gene transfer; Genetics; Computational biology; Biochemistry; Biosynthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002440494,0.0001418341,0.0001937051,0.0001587988,0.00005955857,0.00002977328,0.0001408508,0.00008399584,0.001184428],"category_scores_gemma":[0.0007507568,0.0001204574,0.00008724189,0.0002210431,0.0001183338,0.0001550264,0.00005028698,0.0001534591,0.00007327935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001554447,"about_ca_system_score_gemma":0.00007247129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007112858,"about_ca_topic_score_gemma":0.00001579638,"domain_scores_codex":[0.9987602,0.00001861525,0.0003694367,0.0003245358,0.0003717162,0.0001554949],"domain_scores_gemma":[0.9985293,0.00003671542,0.0003063013,0.0001963041,0.0008802685,0.00005115242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004272333,0.0002082422,0.0005729467,0.00004808698,0.0001179254,0.000003775162,0.00008390587,3.880625e-7,0.9919024,0.0000111165,0.005929427,0.0006946208],"study_design_scores_gemma":[0.0006571877,0.0001056536,0.03652767,0.0000809588,0.00007374581,0.00003521981,0.00001809598,0.00007992201,0.9479637,0.00005119241,0.01428614,0.0001205655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909257,0.00005306942,0.00009092659,0.004968347,0.001482776,0.0003227349,0.0002450538,0.00007803065,0.001833383],"genre_scores_gemma":[0.9889794,0.00002244864,0.0001439278,0.0004396651,0.002640564,0.000004745305,0.004153038,0.00001761627,0.00359857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04393869,"threshold_uncertainty_score":0.9997286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01108275950593331,"score_gpt":0.248035749043943,"score_spread":0.2369529895380097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}