{"id":"W2884095185","doi":"10.1194/jlr.m087056","title":"Intestinal de novo phosphatidylcholine synthesis is required for dietary lipid absorption and metabolic homeostasis","year":2018,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University of Alberta; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Technology Futures","keywords":"Internal medicine; Endocrinology; Chylomicron; Phosphocholine; Phosphatidylcholine; Biology; Lipid metabolism; Intestinal epithelium; Small intestine; Bile acid; Secretion; Chemistry; Very low-density lipoprotein; Cholesterol; Biochemistry; Lipoprotein; Phospholipid; Epithelium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001351362,0.0005325609,0.0003408564,0.0003263505,0.0001719899,0.0005482279,0.0002249757,0.0004113617,0.001029242],"category_scores_gemma":[0.00025578,0.0002849705,0.0003028417,0.0002390399,0.0003665911,0.0003718035,0.0003579965,0.0008726086,0.0005373888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004943598,"about_ca_system_score_gemma":0.0002561317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009861051,"about_ca_topic_score_gemma":0.0009479816,"domain_scores_codex":[0.9997781,0.0000213732,0.00003106421,0.00006491412,0.00005682921,0.00004763175],"domain_scores_gemma":[0.9995437,0.00003871169,0.0001808068,0.00005603617,0.00005550261,0.0001252337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001794911,0.000006159486,0.0005254754,0.00001962898,0.000003381976,0.00004474974,0.000007636593,0.00003428181,0.9985624,0.00006263042,0.000009917287,0.0005442307],"study_design_scores_gemma":[0.00002497039,0.0001207987,0.0196938,0.00001191052,0.00002156177,0.000335015,0.0000469512,0.0007614554,0.9774039,0.00009024011,0.001482102,0.000007379368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908872,0.001496529,0.005346778,0.0001330681,0.00002651203,0.00002404457,0.001018556,0.0001134127,0.0009541026],"genre_scores_gemma":[0.9915343,0.001132796,0.003624537,0.00006062687,0.000009467616,0.00004431962,0.00123951,0.00005773807,0.002296711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001029242,"threshold_uncertainty_score":0.003586829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1068169275183292,"score_gpt":0.3909151779414375,"score_spread":0.2840982504231083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}