{"id":"W2884110752","doi":"10.1055/s-0038-1644925","title":"Targeting mitochondrial and oxidative stress vulnerability of cancer cells to induce apoptosis using natural compounds and extracts","year":2018,"lang":"en","type":"article","venue":"Planta Medica International Open","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"","keywords":"Cancer cell; Oxidative stress; Apoptosis; Cancer; Programmed cell death; Cancer research; Mitochondrion; Biology; Cell; Cell biology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000580364,0.0001943684,0.0001249897,0.0002232588,0.00009813748,0.0001635696,0.0001009265,0.0001575505,0.000918037],"category_scores_gemma":[0.00004364259,0.00005820095,0.0001342304,0.00008974213,0.0001101861,0.0001542392,0.0001536994,0.0002981821,0.0001702928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001538563,"about_ca_system_score_gemma":0.0001304281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001844376,"about_ca_topic_score_gemma":0.0006754259,"domain_scores_codex":[0.9999756,0.000004060675,0.000001686362,0.000006563063,0.000005930432,0.000006126976],"domain_scores_gemma":[0.9999706,0.000004195227,0.000009576695,0.00000406767,0.000004364305,0.000007257244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001083502,0.00004129848,0.0001056422,0.0002477838,0.000009031656,0.00006230446,0.00001329145,0.00007261304,0.991569,0.0002567192,0.0001243981,0.00738954],"study_design_scores_gemma":[0.00004610535,0.0006397624,0.003696227,0.00003906381,0.00003389831,0.0004338313,0.00003095248,0.0002923024,0.9768196,0.0002853529,0.0176752,0.000007747388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9457473,0.03154979,0.01141131,0.0008872939,0.0001022998,0.0001358755,0.0007771332,0.000304302,0.009084815],"genre_scores_gemma":[0.9837188,0.008229791,0.004137061,0.000178827,0.00001739655,0.00005193462,0.0003262633,0.00001563764,0.00332434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000918037,"threshold_uncertainty_score":0.003071129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02206212411870943,"score_gpt":0.3415013633258691,"score_spread":0.3194392392071596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}