{"id":"W2884110883","doi":"10.1016/j.chom.2018.06.017","title":"α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis","year":2018,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":149,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"FP7 People: Marie-Curie Actions; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Marie Curie; University of Calgary; Heart and Stroke Foundation of Canada","keywords":"Sepsis; Staphylococcus aureus; Disseminated intravascular coagulation; Platelet; Microcirculation; Immunology; Coagulation; Biology; Toxin; Staphylococcal infections; Microbiology; Medicine; Pathology; Bacteria; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001709903,0.000356322,0.0004290411,0.0002529236,0.0002986554,0.00008118379,0.0001756643,0.0002801092,0.0003941542],"category_scores_gemma":[0.00007042613,0.0003447161,0.0001125811,0.0003760144,0.0004957978,0.0001971906,0.000179538,0.0003681842,0.0003433757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001531036,"about_ca_system_score_gemma":0.0001173212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001040249,"about_ca_topic_score_gemma":0.00005661547,"domain_scores_codex":[0.998134,0.00005406788,0.0004082375,0.0006154605,0.0002255414,0.0005627173],"domain_scores_gemma":[0.9987672,0.00005826815,0.000205213,0.0004922556,0.0002427796,0.0002342824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004274971,0.0001187843,0.003838839,0.0002621886,0.00004720426,0.0001032338,0.0009611217,2.273355e-7,0.982867,0.00001229066,0.007439043,0.003922557],"study_design_scores_gemma":[0.001297514,0.0002780056,0.02497367,0.0003118302,0.00007547364,0.00002559925,0.0002126373,0.000009500878,0.9533004,0.00001825931,0.01913981,0.0003572846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937329,0.00173371,0.00008347305,0.0002121506,0.0002693237,0.0006344301,0.0000659351,0.0001334346,0.003134693],"genre_scores_gemma":[0.9937351,0.0006442599,0.001773388,0.0006393106,0.000512885,0.00001446092,0.00002571779,0.00007222622,0.002582684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0295666,"threshold_uncertainty_score":0.9999005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01006429806896063,"score_gpt":0.2498514208428836,"score_spread":0.239787122773923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}