{"id":"W2884237425","doi":"10.31031/igrwh.2018.01.000524","title":"Humanized GHR106 Monoclonal Antibody is a Biosimilar GnRH Antagonist","year":2018,"lang":"en","type":"article","venue":"Investigations in Gynecology Research & Womens Health (IGRWH)","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Monoclonal antibody; Biosimilar; Antibody; Antagonist; Receptor; Humanized antibody; Chemistry; Isotype; Immunohistochemistry; Molecular biology; Peptide; Pharmacology; Cancer research; Biology; Internal medicine; Immunology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003455929,0.0002692277,0.0002521632,0.0003554686,0.0001357915,0.0002449303,0.00038097,0.0004910488,0.003968847],"category_scores_gemma":[0.0003018378,0.0001149835,0.0003146257,0.0002255671,0.0002387413,0.0001952969,0.0002505819,0.0006399585,0.001135464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004092917,"about_ca_system_score_gemma":0.0002570706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004772462,"about_ca_topic_score_gemma":0.000383785,"domain_scores_codex":[0.9996904,0.0000639881,0.00002069545,0.00006164637,0.000126489,0.00003676259],"domain_scores_gemma":[0.9998845,0.00002083205,0.0000224353,0.00001780895,0.00002613254,0.00002829069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007227617,0.0001986858,0.0005231015,0.0001894743,0.00002479678,0.0003842536,0.00005049615,0.0001838389,0.9419452,0.0008875851,0.001560373,0.0533294],"study_design_scores_gemma":[0.0006668838,0.007627002,0.008399578,0.00005977945,0.00011325,0.01020308,0.00007574911,0.001403144,0.7773221,0.0005223403,0.1935628,0.00004433124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8921689,0.02388416,0.03226691,0.001501301,0.0008765955,0.0008763643,0.001904901,0.001123087,0.04539791],"genre_scores_gemma":[0.9517353,0.004708088,0.01966892,0.000728568,0.0001649615,0.0002094867,0.002765333,0.00008141227,0.01993795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003968847,"threshold_uncertainty_score":0.01327705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0541017375773233,"score_gpt":0.4277143456931328,"score_spread":0.3736126081158095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}