{"id":"W2884250910","doi":"10.1016/j.celrep.2018.06.056","title":"COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Endosome; Cell biology; Microtubule; Cytoskeleton; Signal transducing adaptor protein; Phosphorylation; Scaffold protein; Biology; Gene silencing; Transport protein; Epidermal growth factor receptor; Chemistry; Receptor; Cell; Signal transduction; Intracellular; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128351,0.000131071,0.0001117511,0.0000396291,0.0001367908,0.0000380315,0.00005544582,0.0001009869,0.00006881302],"category_scores_gemma":[0.00004380516,0.0001239515,0.00006577752,0.00003669789,0.00005477638,0.000003218159,0.00007038408,0.00008647039,0.00001460764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001087604,"about_ca_system_score_gemma":0.00002832801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001701576,"about_ca_topic_score_gemma":0.00001626164,"domain_scores_codex":[0.9991831,0.00002160769,0.0001893436,0.0003402376,0.00008385283,0.0001818401],"domain_scores_gemma":[0.9993835,0.00001079866,0.0001138262,0.0003422622,0.00007030346,0.00007929999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001793902,0.00006007301,0.0004782352,0.00001047066,0.0000199588,0.00005731639,0.00005831165,0.000002426232,0.9909208,0.000106353,0.003555865,0.004712229],"study_design_scores_gemma":[0.0001280622,0.000367763,0.0001742209,0.00001351001,0.00001147462,0.0001650284,0.0000654617,0.00006634629,0.7942139,0.00009587307,0.2045699,0.0001284909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788563,0.0003616585,0.0003844389,0.00008767602,0.0005004638,0.0001222726,0.000001915688,0.0000194459,0.01966587],"genre_scores_gemma":[0.9964369,0.000104849,0.0001062974,0.0002272857,0.0003152033,0.000009413914,0.00005303249,0.00002261979,0.002724385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.201014,"threshold_uncertainty_score":0.5054595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007894706503528802,"score_gpt":0.2354043671362516,"score_spread":0.2275096606327228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}