{"id":"W2884262556","doi":"10.1038/s41598-018-29229-5","title":"Gut Bacterial Microbiota and its Resistome Rapidly Recover to Basal State Levels after Short-term Amoxicillin-Clavulanic Acid Treatment in Healthy Adults","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Lallemand (Canada)","funders":"","keywords":"Resistome; Biology; Lachnospiraceae; Microbiology; Lactobacillus rhamnosus; Gut flora; Metagenomics; Amoxicillin; Microbiome; Antibiotics; Antibiotic resistance; Probiotic; Bacteria; 16S ribosomal RNA; Genetics; Immunology; Firmicutes; Integron","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002046267,0.0003092504,0.0004561711,0.0002791486,0.0001459129,0.0003045027,0.00009111648,0.0003893232,0.0008105966],"category_scores_gemma":[0.0005818005,0.0001518479,0.0002223118,0.0001815001,0.0001340027,0.0001814664,0.0002512594,0.0003281125,0.000176403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001038536,"about_ca_system_score_gemma":0.000102529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006070125,"about_ca_topic_score_gemma":0.000717778,"domain_scores_codex":[0.9998032,0.0000406558,0.0000129175,0.00006341488,0.00004132479,0.00003844598],"domain_scores_gemma":[0.9998186,0.0000231209,0.0000688351,0.0000165722,0.00002563728,0.00004713745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0102674,0.0006698064,0.3851571,0.0002753732,0.0002800088,0.000958729,0.0006464932,0.0002220092,0.5322178,0.00005065918,0.0004696688,0.06878495],"study_design_scores_gemma":[0.00002226175,0.001608535,0.9889457,0.00001346596,0.00005734515,0.0004867851,0.0002476799,0.0002513079,0.007838056,0.00004455227,0.000477273,0.00000708265],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990209,0.000511097,0.0001604972,0.00003442495,0.000005840012,0.000007404587,0.00009492163,0.00001026223,0.0001546207],"genre_scores_gemma":[0.9988293,0.0002442325,0.0002366388,0.00006128524,0.00000819037,0.00001364768,0.0002330038,0.000003994783,0.0003697598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008105966,"threshold_uncertainty_score":0.002711713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01456885112574956,"score_gpt":0.2759871223291593,"score_spread":0.2614182712034097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}