{"id":"W2884262556","doi":"10.1038/s41598-018-29229-5","title":"Gut Bacterial Microbiota and its Resistome Rapidly Recover to Basal State Levels after Short-term Amoxicillin-Clavulanic Acid Treatment in Healthy Adults","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Lallemand (Canada)","funders":"","keywords":"Resistome; Biology; Lachnospiraceae; Microbiology; Lactobacillus rhamnosus; Gut flora; Metagenomics; Amoxicillin; Microbiome; Antibiotics; Antibiotic resistance; Probiotic; Bacteria; 16S ribosomal RNA; Genetics; Immunology; Firmicutes; Integron","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006424329,0.0002804949,0.0002998794,0.0001912351,0.0001972508,0.0001454882,0.0001221906,0.0001741359,0.0001545346],"category_scores_gemma":[0.00004132313,0.0002519528,0.000081577,0.000228344,0.0001540788,0.00001481506,0.0001528542,0.00007866396,0.00005523309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001107775,"about_ca_system_score_gemma":0.0004251771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005439776,"about_ca_topic_score_gemma":0.003077611,"domain_scores_codex":[0.9971349,0.00009368576,0.0006458669,0.001323111,0.0001551224,0.0006472779],"domain_scores_gemma":[0.9986073,0.000005751698,0.0001467613,0.000764782,0.0001680115,0.0003073663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001367765,0.000112389,0.003861665,0.00004277044,0.00001775571,0.0001158581,0.0004789287,4.726298e-7,0.9902701,3.940101e-7,0.002653126,0.001078755],"study_design_scores_gemma":[0.001411668,0.002709302,0.2243923,0.000157183,0.00002135175,0.000253918,0.00003602103,0.000004718517,0.6706945,0.00005485328,0.09961005,0.0006541549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951473,0.0004939851,0.00001277278,0.0002130696,0.003130419,0.0007823554,0.0001167884,0.00001394373,0.00008929848],"genre_scores_gemma":[0.996517,0.0000701235,0.0003064962,0.0003261244,0.000309196,0.00004839054,0.0002233641,0.00003193524,0.002167346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3195756,"threshold_uncertainty_score":0.9999933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01456885112574956,"score_gpt":0.2759871223291593,"score_spread":0.2614182712034097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}