{"id":"W2884345652","doi":"10.1007/s40521-018-0177-1","title":"Mechanism of Synthetic Peptide Immuno-Regulatory Epitopes and Their Clinical Efficacy in the Treatment of Allergic Disease","year":2018,"lang":"en","type":"article","venue":"Current Treatment Options in Allergy","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Ragweed; Medicine; Clinical trial; Immunotherapy; Epitope; Allergy; Immunology; Placebo; Desensitization (medicine); Clinical endpoint; Immune system; Internal medicine; Pharmacology; Antigen; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000655781,0.0001571982,0.000241814,0.0001794623,0.00008043901,0.0002513921,0.0002789776,0.0002746829,0.001543186],"category_scores_gemma":[0.000275193,0.00006071494,0.0002316151,0.0001119903,0.0002485647,0.0002889592,0.0001107749,0.000544487,0.0002297821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008362011,"about_ca_system_score_gemma":0.0001114167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006153266,"about_ca_topic_score_gemma":0.00005960902,"domain_scores_codex":[0.9998821,0.00005516093,0.000009282682,0.00001246216,0.00001749579,0.00002339852],"domain_scores_gemma":[0.9999329,0.00002844866,0.00001468512,0.000006060513,0.000007167077,0.00001082759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01592424,0.004345528,0.002126763,0.001624707,0.000141965,0.0008371485,0.000161317,0.002295227,0.466065,0.00626305,0.001260784,0.4989544],"study_design_scores_gemma":[0.01238116,0.1720319,0.03372038,0.0005461399,0.0007930928,0.008081395,0.0002882883,0.006261761,0.6517701,0.004822029,0.1092141,0.00008963452],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8758416,0.1128739,0.003798022,0.0005135012,0.0003065545,0.0001897283,0.0001557822,0.00006252364,0.006258321],"genre_scores_gemma":[0.9777533,0.01890291,0.001486199,0.0001800225,0.0001382648,0.00008188911,0.0001552329,0.000007073362,0.001295049],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001543186,"threshold_uncertainty_score":0.005162477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05308864065285741,"score_gpt":0.3375052119849729,"score_spread":0.2844165713321155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}