{"id":"W2884353270","doi":"10.18632/oncotarget.25797","title":"The vulnerability of RB loss in breast cancer: Targeting a void in cell cycle control","year":2018,"lang":"en","type":"editorial","venue":"Oncotarget","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"National Cancer Institute","keywords":"Breast cancer; Medicine; Cell cycle; Cancer research; Cell; Oncology; Internal medicine; Cancer; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00191884,0.0004605372,0.001195212,0.0001954391,0.0000837563,0.00002274581,0.0004149824,0.001048804,0.0001891568],"category_scores_gemma":[0.001066728,0.000367657,0.0002543306,0.0004887779,0.0003612167,0.0000575226,0.0001131327,0.002205653,0.00003383638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001421345,"about_ca_system_score_gemma":0.002285196,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008884856,"about_ca_topic_score_gemma":0.003992612,"domain_scores_codex":[0.9960053,0.0003780497,0.001120639,0.0007526368,0.00100249,0.0007408755],"domain_scores_gemma":[0.9970639,0.0008258864,0.0005831353,0.0008439922,0.0005176621,0.0001654597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002240043,0.0004375078,0.01912098,0.0005541297,0.00008469513,0.0001319205,0.0004094033,0.0002669975,0.004568063,0.000003286269,0.971817,0.0003659459],"study_design_scores_gemma":[0.01431888,0.0004666358,0.007152351,0.001593864,0.0002357071,0.00001124717,0.0001368029,0.0008779758,0.001783554,0.0002622562,0.9724932,0.0006675532],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.1807081,0.01167945,0.00005772901,0.002680927,0.7967653,0.002506819,0.002816242,0.00009139792,0.002693938],"genre_scores_gemma":[0.4860477,0.001720427,0.0001716701,0.0001772187,0.510506,0.0002847398,0.000413833,0.0001973816,0.0004810304],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.3053396,"threshold_uncertainty_score":0.9998775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003586190352102446,"score_gpt":0.2591076201657224,"score_spread":0.25552142981362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}