{"id":"W2884353270","doi":"10.18632/oncotarget.25797","title":"The vulnerability of RB loss in breast cancer: Targeting a void in cell cycle control","year":2018,"lang":"en","type":"editorial","venue":"Oncotarget","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"National Cancer Institute","keywords":"Breast cancer; Medicine; Cell cycle; Cancer research; Cell; Oncology; Internal medicine; Cancer; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003385601,0.002728676,0.002463589,0.001631653,0.001131542,0.003500902,0.002593561,0.01059544,0.005521236],"category_scores_gemma":[0.006497697,0.0008380481,0.001715814,0.0007233074,0.001925304,0.003028886,0.001404173,0.01927317,0.003789244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001550055,"about_ca_system_score_gemma":0.001418041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005138328,"about_ca_topic_score_gemma":0.001508616,"domain_scores_codex":[0.998466,0.0002627145,0.0002187812,0.0002095955,0.0006924662,0.0001504065],"domain_scores_gemma":[0.9951805,0.002433203,0.0003698356,0.0001574871,0.001199745,0.0006592919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001327851,0.00002445046,0.00004904301,0.0006166747,0.00004459263,0.0002212186,0.00001753007,0.00004772417,0.0004776815,0.001079338,0.9725468,0.02474219],"study_design_scores_gemma":[0.00009661853,0.00008165713,0.0002712338,0.0003492489,0.0001042552,0.0005542058,0.00002967704,0.000143872,0.0005711075,0.001650935,0.9961239,0.0000233832],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.0001970561,0.05468899,0.0004615095,0.07007858,0.8723963,0.00002069863,0.0001082045,0.0001253955,0.001923208],"genre_scores_gemma":[0.001399683,0.03456508,0.000236435,0.03016773,0.9243472,0.00002625685,0.00005225117,0.00003649452,0.009168835],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.01059544,"threshold_uncertainty_score":0.01847041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003586190352102446,"score_gpt":0.2591076201657224,"score_spread":0.25552142981362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}