{"id":"W2884798135","doi":"10.1128/jvi.00680-18","title":"Porcine Adenovirus Type 3 E3 Encodes a Structural Protein Essential for Capsid Stability and Production of Infectious Progeny Virions","year":2018,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Capsid; Biology; Lytic cycle; Virology; Mastadenovirus; Molecular biology; Adenoviridae; Viral replication; Virus; Gene; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001533663,0.0002644241,0.0001582071,0.0001722273,0.0002240536,0.0003514679,0.0001234557,0.0002883534,0.0008501508],"category_scores_gemma":[0.0002278659,0.0001273902,0.0004210303,0.0001490541,0.000342229,0.0002207639,0.000214517,0.0004005924,0.0005553317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003434506,"about_ca_system_score_gemma":0.0003982995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000893329,"about_ca_topic_score_gemma":0.0007458185,"domain_scores_codex":[0.9999126,0.00001273494,0.000007809276,0.00001496791,0.00002793059,0.00002394872],"domain_scores_gemma":[0.9998469,0.00003776552,0.00003935439,0.00002078329,0.00001606949,0.00003908356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007117088,0.000010143,0.000742103,0.00002579372,0.000003724414,0.0001092457,0.00001598569,0.00004446698,0.9975557,0.0001321728,0.00004318429,0.001246373],"study_design_scores_gemma":[0.00003506468,0.0005333406,0.04124528,0.0000177052,0.00003511639,0.003902219,0.0001154501,0.001842131,0.9405839,0.0004381233,0.01123232,0.00001925668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868477,0.0009725392,0.009356554,0.0001064445,0.00005560751,0.00002804563,0.0005522186,0.00009869868,0.001982095],"genre_scores_gemma":[0.991844,0.0004826129,0.005225822,0.00004107337,0.000008262027,0.000009806966,0.0008415726,0.00002753195,0.001519206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000893329,"threshold_uncertainty_score":0.002843976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01635955761449704,"score_gpt":0.3166473355161742,"score_spread":0.3002877779016772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}