{"id":"W2884819324","doi":"10.1039/c8sc02291g","title":"Bright insights into palladium-triggered local chemotherapy","year":2018,"lang":"en","type":"article","venue":"Chemical Science","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"H2020 Marie Skłodowska-Curie Actions; H2020 European Research Council; Horizon 2020 Framework Programme; Cancer Research UK; University of Edinburgh; Engineering and Physical Sciences Research Council; Melanoma Research Alliance; Medical Research Council; L'Oreal USA","keywords":"Palladium; Chemotherapy; Chemistry; Medicine; Internal medicine; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001583055,0.0001224173,0.0001820967,0.00005503071,0.0001407507,0.00002888648,0.0002054402,0.00005508395,0.000453811],"category_scores_gemma":[0.00007428762,0.00007892657,0.00006124576,0.0006064866,0.001974888,0.00008604376,0.00005955463,0.00009079052,0.0002472784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001894216,"about_ca_system_score_gemma":0.0001835957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004698076,"about_ca_topic_score_gemma":0.000002828573,"domain_scores_codex":[0.9986919,0.000008009301,0.0001483319,0.0004091965,0.0004220039,0.0003206017],"domain_scores_gemma":[0.9990909,0.00003128392,0.00003363612,0.0003358586,0.0001317706,0.0003765394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001815255,0.0004412594,0.001015083,0.00002542912,0.00003628556,0.00005978265,0.0008367053,1.69964e-7,0.7800615,0.001949844,0.002277248,0.2131151],"study_design_scores_gemma":[0.001221004,0.0001820929,0.005045554,0.00003364862,0.00002055917,0.00003764289,0.00002790928,0.0003941144,0.9444693,0.001567826,0.04688139,0.0001189136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989625,0.0002767889,0.001448136,0.001657176,0.0001276421,0.0001727322,6.294587e-7,0.0000583172,0.006633616],"genre_scores_gemma":[0.9935248,0.00002487692,0.004237515,0.001723654,0.000253962,0.0000069137,0.000004200402,0.000008573366,0.0002154925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2129962,"threshold_uncertainty_score":0.7276556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01118378068766841,"score_gpt":0.2837379491487608,"score_spread":0.2725541684610924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}