{"id":"W2884963629","doi":"10.1002/slct.201801151","title":"Synthesis of 2‐Aryl‐ and 2‐Haloarylbenzimidazole‐ <i>N</i> 1‐acetamido Conjugates and a Preliminary Evaluation of Their Antifungal Properties","year":2018,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University; Memorial University of Newfoundland","funders":"","keywords":"Moiety; Aryl; Fluconazole; Chemistry; Amphotericin B; Aspergillus fumigatus; Stereochemistry; Conjugate; Candida albicans; Antifungal; Agarose; Minimum inhibitory concentration; Combinatorial chemistry; In vitro; Organic chemistry; Chromatography; Biochemistry; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004794272,0.0002009114,0.0003834078,0.00001913469,0.00007339187,0.00001580385,0.0001343504,0.0001719822,0.0003068426],"category_scores_gemma":[0.0006872492,0.0001384596,0.00005930815,0.00008236348,0.0006650841,0.0000687701,0.00009723937,0.0000929157,8.111811e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002039116,"about_ca_system_score_gemma":0.00006131793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002659369,"about_ca_topic_score_gemma":0.000002073411,"domain_scores_codex":[0.9989154,0.00002828804,0.0002860955,0.0003433089,0.0002340885,0.0001927721],"domain_scores_gemma":[0.9989035,0.0002924756,0.0002116517,0.000238553,0.0002927029,0.00006113181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000233586,0.0001281814,0.01081506,0.0004758264,0.00007243126,3.089028e-7,0.0001071735,3.204322e-7,0.9612306,0.000002989008,0.0000427433,0.02689075],"study_design_scores_gemma":[0.0002814131,0.00008866905,0.005588719,0.0002509022,0.0001371818,0.00002321483,0.0002091629,0.001251312,0.9918649,0.00009739248,0.00003792536,0.0001692183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920236,0.002071382,0.000001176319,0.00004644068,0.00001070703,0.00008970647,0.00004098613,0.00002894985,0.005687043],"genre_scores_gemma":[0.9995884,0.0001855229,0.0000473611,0.000008483556,0.00008850245,0.00003281665,0.000005943605,0.00001262652,0.00003030822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03063426,"threshold_uncertainty_score":0.5646219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03377288196990114,"score_gpt":0.2369184025164065,"score_spread":0.2031455205465054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}