{"id":"W2884963629","doi":"10.1002/slct.201801151","title":"Synthesis of 2‐Aryl‐ and 2‐Haloarylbenzimidazole‐ <i>N</i> 1‐acetamido Conjugates and a Preliminary Evaluation of Their Antifungal Properties","year":2018,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University; Memorial University of Newfoundland","funders":"","keywords":"Moiety; Aryl; Fluconazole; Chemistry; Amphotericin B; Aspergillus fumigatus; Stereochemistry; Conjugate; Candida albicans; Antifungal; Agarose; Minimum inhibitory concentration; Combinatorial chemistry; In vitro; Organic chemistry; Chromatography; Biochemistry; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001289579,0.0004801642,0.0003287494,0.0001474901,0.0001255812,0.000190137,0.0003652645,0.0002209566,0.001164561],"category_scores_gemma":[0.0001576954,0.0001506744,0.0001606887,0.0002412275,0.0001197956,0.0001609437,0.000152716,0.0002554011,0.0005424406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002622183,"about_ca_system_score_gemma":0.0002754427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006341375,"about_ca_topic_score_gemma":0.001308846,"domain_scores_codex":[0.9999123,0.00001656708,0.000008674244,0.00001505469,0.00002526313,0.00002212662],"domain_scores_gemma":[0.999934,0.000006812751,0.00001977937,0.000008004464,0.000017632,0.00001378244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001546241,0.00008538191,0.0001747736,0.0001819606,0.00001167252,0.0001938375,0.0000451642,0.0008639371,0.9890261,0.0003070565,0.0001795567,0.00877605],"study_design_scores_gemma":[0.00006970949,0.001182349,0.001908547,0.0000111224,0.00003160566,0.0003856156,0.00001629207,0.001132782,0.9865206,0.00004752175,0.008678214,0.00001556591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9708114,0.004359962,0.01408906,0.0001450932,0.00007891646,0.0003061926,0.0007747755,0.0001774101,0.009257077],"genre_scores_gemma":[0.9803541,0.003053706,0.01162363,0.00008408562,0.00001899898,0.0001591399,0.0007274989,0.00002984891,0.003948926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001164561,"threshold_uncertainty_score":0.003895819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03377288196990114,"score_gpt":0.2369184025164065,"score_spread":0.2031455205465054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}