{"id":"W2885137196","doi":"10.1128/iai.00092-18","title":"Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract","year":2018,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; Government of Canada; University of Toronto; National Institute of Allergy and Infectious Diseases; McMaster University","keywords":"Biology; Bacterial adhesin; Carcinoembryonic antigen; Immunology; Cell adhesion molecule; Neisseria gonorrhoeae; Antigen; Tumor necrosis factor alpha; Microbiology; Gene; Cancer; Escherichia coli; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001076602,0.0001402737,0.0001789626,0.000286958,0.00008188028,0.000243742,0.00007309079,0.0002209636,0.000754922],"category_scores_gemma":[0.0002573532,0.0001485454,0.000128936,0.0001237861,0.0001837467,0.0001162982,0.0001804786,0.0002845665,0.0001256512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001160121,"about_ca_system_score_gemma":0.00008311577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004714273,"about_ca_topic_score_gemma":0.0006363559,"domain_scores_codex":[0.9998068,0.00003110114,0.00001447338,0.00004257416,0.00003231399,0.00007280279],"domain_scores_gemma":[0.9998696,0.00002061087,0.00003876391,0.00001124515,0.00001266825,0.00004719582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002015581,0.0000306909,0.01178293,0.00001979776,0.000007295653,0.0001058699,0.00004078451,0.00001515382,0.9866809,0.00003030229,0.00001533561,0.001069367],"study_design_scores_gemma":[0.00001473457,0.0009463523,0.8064062,0.00001260235,0.00003961168,0.001434007,0.0002790818,0.0005516738,0.1895074,0.00006522657,0.0007323372,0.00001090941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993438,0.0002105072,0.0001235533,0.00000900446,0.000002121524,0.000005367054,0.00004932816,0.000003189192,0.0002530994],"genre_scores_gemma":[0.9991559,0.0002069841,0.0001670202,0.0000171693,0.000002555244,0.00001026927,0.0001047755,0.000002152466,0.00033326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000754922,"threshold_uncertainty_score":0.002525449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03525373361511247,"score_gpt":0.3017657654620075,"score_spread":0.266512031846895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}