{"id":"W2885137196","doi":"10.1128/iai.00092-18","title":"Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract","year":2018,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; Government of Canada; University of Toronto; National Institute of Allergy and Infectious Diseases; McMaster University","keywords":"Biology; Bacterial adhesin; Carcinoembryonic antigen; Immunology; Cell adhesion molecule; Neisseria gonorrhoeae; Antigen; Tumor necrosis factor alpha; Microbiology; Gene; Cancer; Escherichia coli; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000373476,0.0001777374,0.0002755472,0.0002363107,0.0008890252,0.00005895879,0.00008484443,0.00008328294,0.0003053075],"category_scores_gemma":[0.0001276977,0.0001110406,0.0001837638,0.000557516,0.0002417265,0.0001198475,0.00007938051,0.0003158604,0.00003321984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004129557,"about_ca_system_score_gemma":0.00002031212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001501647,"about_ca_topic_score_gemma":0.000312302,"domain_scores_codex":[0.9987673,0.0002588512,0.0004438591,0.0002623437,0.00008938118,0.0001783224],"domain_scores_gemma":[0.9988189,0.00008557244,0.0002092936,0.0005817367,0.0002278504,0.00007661212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003385067,0.0002855197,0.2342546,0.00002740223,0.00004632892,6.801149e-7,0.001061106,0.000006214192,0.7637041,0.00002828872,0.00006570932,0.0004862116],"study_design_scores_gemma":[0.0004710967,0.0003543227,0.7461731,0.0001087353,0.00008796543,0.00003005919,0.0004299851,0.00004589867,0.2516859,0.00002258878,0.0004853953,0.0001049454],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997573,0.00006699139,0.0002113334,0.0002682386,0.0001544442,0.0003769186,0.000007919358,0.00006442485,0.001276696],"genre_scores_gemma":[0.9991409,0.00008402336,0.00001544754,0.00008138407,0.0001382686,0.00001864159,0.00002728375,0.00001749959,0.0004765314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5120181,"threshold_uncertainty_score":0.6837752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03525373361511247,"score_gpt":0.3017657654620075,"score_spread":0.266512031846895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}