{"id":"W2885235949","doi":"10.1016/j.euroneuro.2018.07.098","title":"Adjunctive S-adenosylmethionine (SAMe) in treating non-remittent major depressive disorder: An 8-week double-blind, randomized, controlled trial,","year":2018,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Health and Medical Research Council","keywords":"Placebo; Major depressive disorder; Internal medicine; Randomized controlled trial; Rating scale; Depression (economics); Medicine; Placebo-controlled study; Adverse effect; Oncology; Psychiatry; Psychology; Double blind; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002708931,0.0005851993,0.002228433,0.0008537357,0.0002487882,0.00007898592,0.0005083774,0.0001615922,0.0008876974],"category_scores_gemma":[0.0006989834,0.0004336124,0.0005228237,0.0008239876,0.0007865934,0.0002403796,0.0002190713,0.001253973,0.0005126362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008799857,"about_ca_system_score_gemma":0.000176068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001600127,"about_ca_topic_score_gemma":0.00005304146,"domain_scores_codex":[0.9917291,0.004080275,0.001449399,0.001196165,0.000573479,0.0009715804],"domain_scores_gemma":[0.9968265,0.001029254,0.0004740373,0.0006703775,0.0004871137,0.0005126984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9278163,0.002557234,0.0003964677,0.00003224602,0.0005382295,0.001638595,0.0008111228,0.00001594748,0.05958259,0.00002568099,0.001405124,0.005180466],"study_design_scores_gemma":[0.9843993,0.006880227,0.003264582,0.00006528245,0.0006837004,0.0001276741,0.0001184801,0.0016104,0.0006565341,0.00001499634,0.001811708,0.0003671407],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.955994,0.0005284253,0.0001165769,0.001658874,0.001755105,0.01045045,0.000005844198,0.0002237625,0.02926693],"genre_scores_gemma":[0.9888871,0.0005486123,0.0002150861,0.002714234,0.002330696,0.000766578,0.00004642024,0.0002411193,0.004250174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05892606,"threshold_uncertainty_score":0.9998116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03729040959467223,"score_gpt":0.3626908306888081,"score_spread":0.3254004210941359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}