{"id":"W2885306014","doi":"10.3892/or.2018.6621","title":"SET7/9 promotes hepatocellular carcinoma progression through regulation of E2F1","year":2018,"lang":"en","type":"article","venue":"Oncology Reports","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fundamental Research Funds for the Central Universities; Government of Jiangsu Province; Southeast University; National Natural Science Foundation of China; Saskatchewan Health Research Foundation","keywords":"E2F1; Downregulation and upregulation; Biology; Cancer research; E2F; Cell cycle; Cyclin D1; Histone H3; Cyclin E; Molecular biology; Histone; Cell; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003854943,0.0001182096,0.0001812982,0.00003082191,0.00007949899,0.000005996246,0.00006388479,0.0002912525,0.0000439156],"category_scores_gemma":[0.0001213298,0.000107054,0.00006746526,0.00008963337,0.0002009058,0.000005041863,0.00008005296,0.00005383783,0.000003845925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002079459,"about_ca_system_score_gemma":0.0001636592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002286729,"about_ca_topic_score_gemma":0.00001664607,"domain_scores_codex":[0.9988337,0.00009138315,0.0004067527,0.0003538334,0.0001411587,0.0001732316],"domain_scores_gemma":[0.9988217,0.000009857173,0.0004261738,0.0004246877,0.0002720664,0.00004555217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003162559,0.0000903673,0.184376,0.00001541239,0.00001697467,0.00002247385,0.0001248167,0.000002908256,0.809609,0.00004001797,0.0003037498,0.00536667],"study_design_scores_gemma":[0.0001831731,0.001294683,0.03954866,0.00001331943,0.00002238998,0.000067688,0.00001583501,0.0001228277,0.9065726,0.001595453,0.05046735,0.00009597924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883833,0.0009690933,0.001823388,0.0001023431,0.0003422391,0.00030633,0.000002041777,0.00001230366,0.008058959],"genre_scores_gemma":[0.9934554,0.00004257725,0.005523917,0.00002884169,0.0003616864,0.00002256619,0.0001403652,0.00001833164,0.0004062894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1448273,"threshold_uncertainty_score":0.4365535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01935044419616859,"score_gpt":0.3148208696324003,"score_spread":0.2954704254362317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}