{"id":"W2885401753","doi":"10.1371/journal.pgen.1007488","title":"Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries","year":2018,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; Canadian Institutes of Health Research; School of Medicine and Public Health, University of Wisconsin-Madison; University of Wisconsin Carbone Cancer Center; University of Wisconsin-Madison; National Cancer Institute; National Science Foundation; National Institutes of Health; University of Melbourne","keywords":"Biology; Oocyte; Homeobox; Cell biology; Population; Follicle; Endocrinology; Internal medicine; Genetics; Embryo; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001438418,0.0001288918,0.000233766,0.00007476902,0.0001011896,0.00001347215,0.00007748527,0.0001270083,0.00002274298],"category_scores_gemma":[0.00003241122,0.0001144689,0.00002200099,0.00006197237,0.0001282141,0.0001132388,0.0001218233,0.00008392091,0.000007496033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001459684,"about_ca_system_score_gemma":0.00001364396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004940557,"about_ca_topic_score_gemma":0.0002055466,"domain_scores_codex":[0.9990532,0.0001403286,0.0003029201,0.0002603784,0.00004144128,0.0002016909],"domain_scores_gemma":[0.9995049,0.00002797877,0.0001300456,0.0002467559,0.00007164055,0.0000187033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001022105,0.00007689103,0.1047865,0.0001698943,0.00002332069,0.00000107142,0.002538277,0.000002157023,0.8913919,0.00001022482,0.000002436207,0.0008951108],"study_design_scores_gemma":[0.001112064,0.0001762134,0.1806442,0.000138523,0.00001551383,0.00002520799,0.000184067,0.00008343029,0.817391,0.00005821947,0.00005659831,0.0001149323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965848,0.002543719,0.0001698494,0.00004422331,0.0001536259,0.0003778759,0.00005890957,0.00002193494,0.00004505198],"genre_scores_gemma":[0.9993187,0.000172912,0.0001749092,0.00000445808,0.00003703692,0.00001519483,0.00003115163,0.00001495641,0.0002307395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0758577,"threshold_uncertainty_score":0.4667906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01104699578991958,"score_gpt":0.227022890779827,"score_spread":0.2159758949899074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}