{"id":"W2885409152","doi":"10.1371/journal.pone.0201826","title":"ATP competes with PIP2 for binding to gelsolin","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Hungarian Science Foundation; Emberi Eroforrások Minisztériuma; Hungarian Scientific Research Fund; Agency for Science, Technology and Research","keywords":"Gelsolin; Actin; Cell biology; Biology; Biophysics; Phosphatidylinositol; Biochemistry; Cytosol; MDia1; Actin cytoskeleton; Cytoskeleton; Cell; Kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002367817,0.0003845693,0.0004105484,0.0001540057,0.0003238367,0.0006580587,0.000720347,0.0005846541,0.002445356],"category_scores_gemma":[0.0005523346,0.000381515,0.0001756878,0.0002672929,0.0004007402,0.0005757441,0.000382987,0.0009529495,0.0006973213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008637671,"about_ca_system_score_gemma":0.0005496699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003441892,"about_ca_topic_score_gemma":0.003206738,"domain_scores_codex":[0.9994211,0.00007669611,0.00004506135,0.0001784456,0.0001685634,0.0001101624],"domain_scores_gemma":[0.9996087,0.0002002913,0.00005813336,0.00003979787,0.00004364364,0.00004949941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002042029,0.00004462816,0.0002769584,0.0001051266,0.000009429864,0.0001433112,0.0000428206,0.0002413137,0.9966826,0.0007123223,0.0001826747,0.001354611],"study_design_scores_gemma":[0.00001721153,0.0000575775,0.001879664,0.000008983242,0.000007492614,0.0001371497,0.00003028744,0.004393888,0.9902914,0.0001529982,0.003010218,0.00001319459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819565,0.001899387,0.008544531,0.0004365416,0.000112558,0.00005612461,0.0007207657,0.0001386435,0.00613486],"genre_scores_gemma":[0.9893596,0.0007416273,0.004426766,0.000140385,0.00001885319,0.00008796676,0.0009395182,0.000066771,0.004218466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003441892,"threshold_uncertainty_score":0.008180559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03427280522745809,"score_gpt":0.2449658325619629,"score_spread":0.2106930273345048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}