{"id":"W2885550272","doi":"10.1016/j.cell.2018.07.033","title":"Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection","year":2018,"lang":"en","type":"article","venue":"Cell","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":229,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Public Health Agency of Canada","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Epitope; Ebola virus; Biology; Virology; Monoclonal antibody; Neutralization; Antibody; Ebolavirus; Glycoprotein; Glycan; Epitope mapping; Immune system; Virus; Immunology; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002921757,0.0001147573,0.00050065,0.0005309795,0.0001161258,0.00002947527,0.00006186543,0.00007773939,0.00006441056],"category_scores_gemma":[0.0001487382,0.00008151428,0.0001986644,0.000835355,0.00007529117,0.00004641138,0.00004442666,0.0001129011,0.0000868131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005166727,"about_ca_system_score_gemma":0.00003581295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005799931,"about_ca_topic_score_gemma":0.0003225977,"domain_scores_codex":[0.9990205,0.00006997498,0.0002397327,0.0001898624,0.0002748558,0.0002050562],"domain_scores_gemma":[0.9991287,0.00005493522,0.00009381089,0.0002504883,0.0003665531,0.0001055223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002871463,0.0002820692,0.01070994,0.005009116,0.001633797,0.00001798709,0.0005302779,0.0001008182,0.9787995,0.00006278345,0.002057096,0.000509486],"study_design_scores_gemma":[0.0006816237,0.0006057068,0.09235826,0.001057891,0.001495388,0.00001385129,0.0002549019,0.002332609,0.9005355,0.00001760262,0.0004847269,0.0001619698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924631,0.0004991887,0.001924638,0.0001875136,0.0001239693,0.0008830785,0.00003680457,0.00004125753,0.00384041],"genre_scores_gemma":[0.9972566,0.00006149226,0.0001840127,0.0001337323,0.0001090281,0.00005607936,0.00002341295,0.00001073943,0.002164863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08164832,"threshold_uncertainty_score":0.3324056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03009648041645223,"score_gpt":0.3125560180241611,"score_spread":0.2824595376077088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}