{"id":"W2885636345","doi":"10.3390/vaccines6030051","title":"Cytokines IL-17, TNF and IFN-γ Alter the Expression of Antimicrobial Peptides and Proteins Disparately: A Targeted Proteomics Analysis using SOMAscan Technology","year":2018,"lang":"en","type":"article","venue":"Vaccines","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Proteomics; Tumor necrosis factor alpha; Antimicrobial; Antimicrobial peptides; Protein expression; Cytokine; Immunology; Biology; Microbiology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001654079,0.0002573585,0.0005034815,0.0003478675,0.0004397998,0.00003890544,0.0001938051,0.0002507267,0.00006586782],"category_scores_gemma":[0.0000495331,0.0001664542,0.00009353308,0.0004879172,0.0007138741,0.0001665138,0.0002817413,0.0001816796,0.000004617422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001019389,"about_ca_system_score_gemma":0.0000340475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003224619,"about_ca_topic_score_gemma":0.0002432516,"domain_scores_codex":[0.9988066,0.0001111655,0.0003368006,0.0003819363,0.00002760529,0.000335923],"domain_scores_gemma":[0.9992087,0.00005334387,0.0002698365,0.0003105791,0.0001387716,0.00001873301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000195048,0.00005392123,0.01174381,0.00003835397,0.0003053478,0.000001134114,0.0004385009,0.00001054446,0.9858283,0.00006919906,0.0007407518,0.0005751155],"study_design_scores_gemma":[0.0006097502,0.0001536139,0.009531308,0.00008917696,0.0003101049,0.00006911158,0.0004456458,0.00006728094,0.9877927,0.000147766,0.000566497,0.000217029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969724,0.0006202791,0.001026479,0.0006141604,0.0001088589,0.0004838751,0.00008848,0.00005553668,0.00002990187],"genre_scores_gemma":[0.9969829,0.000117657,0.002233589,0.00008292828,0.00009202761,0.00001792322,0.0000238706,0.00002079489,0.0004283108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002212502,"threshold_uncertainty_score":0.6787806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072124572293419,"score_gpt":0.2358382460369844,"score_spread":0.2251170003140502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}