{"id":"W2885636345","doi":"10.3390/vaccines6030051","title":"Cytokines IL-17, TNF and IFN-γ Alter the Expression of Antimicrobial Peptides and Proteins Disparately: A Targeted Proteomics Analysis using SOMAscan Technology","year":2018,"lang":"en","type":"article","venue":"Vaccines","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Proteomics; Tumor necrosis factor alpha; Antimicrobial; Antimicrobial peptides; Protein expression; Cytokine; Immunology; Biology; Microbiology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001617667,0.0003386351,0.0003038284,0.0002739989,0.0001259924,0.0003298284,0.0001162014,0.0003110381,0.000575433],"category_scores_gemma":[0.0001157189,0.0001442208,0.0003179896,0.0002330332,0.0001476052,0.0002177586,0.0001653633,0.0003721151,0.0002159618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067333,"about_ca_system_score_gemma":0.00009421998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001257134,"about_ca_topic_score_gemma":0.0002111362,"domain_scores_codex":[0.999854,0.00001525147,0.00001206383,0.00003757993,0.00005292932,0.00002822666],"domain_scores_gemma":[0.9999288,0.00001522442,0.00002653935,0.000006090106,0.00001368376,0.000009526651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004402931,0.000005092191,0.000240047,0.0000148257,0.000003664904,0.00001991346,0.000006959045,0.00001278465,0.9992392,0.000006022711,0.000005791036,0.000401675],"study_design_scores_gemma":[0.000005756743,0.0001763707,0.01782475,0.00000805434,0.00002832504,0.0003114024,0.00004790613,0.0008525439,0.979947,0.00003594185,0.0007561462,0.00000586025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942079,0.001394477,0.003383746,0.00005606211,0.00002230546,0.00001995735,0.0004075738,0.00003280801,0.0004752894],"genre_scores_gemma":[0.9843758,0.002481563,0.009794645,0.0001989683,0.00001970119,0.00008221441,0.001015593,0.00002460688,0.002007034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000575433,"threshold_uncertainty_score":0.001924992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072124572293419,"score_gpt":0.2358382460369844,"score_spread":0.2251170003140502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}