{"id":"W2885648903","doi":"10.3389/fimmu.2018.01743","title":"Differential Mechanisms of Septic Human Pulmonary Microvascular Endothelial Cell Barrier Dysfunction Depending on the Presence of Neutrophils","year":2018,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Western University; Canadian Lung Association; Lawson Health Research Institute; Heart and Stroke Foundation of Canada","keywords":"Medicine; Immunology; Endothelial stem cell; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003156475,0.0002403267,0.0003417543,0.0002220788,0.00007913774,0.000307999,0.00016534,0.0003053431,0.000726466],"category_scores_gemma":[0.000261513,0.0001103936,0.0002291129,0.0001375323,0.0001659359,0.0002882223,0.0002324788,0.0004061592,0.0001965903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001988933,"about_ca_system_score_gemma":0.0001148795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001499922,"about_ca_topic_score_gemma":0.0001359348,"domain_scores_codex":[0.9996593,0.0001264123,0.00003229123,0.0000449615,0.00006521527,0.00007183073],"domain_scores_gemma":[0.9998828,0.00001959105,0.00003753137,0.00001640544,0.00002114051,0.00002250301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001387272,0.00009705147,0.002912562,0.0001836287,0.00002387391,0.0005957605,0.00009871434,0.0001265883,0.9893264,0.0004585203,0.0001115913,0.004678131],"study_design_scores_gemma":[0.0001405397,0.002409143,0.1064934,0.00006687601,0.0001140076,0.003854105,0.0003320289,0.003223719,0.8794535,0.0006087669,0.003282564,0.00002119788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873636,0.007523911,0.003655535,0.0001439609,0.00003166989,0.00004736166,0.0001872397,0.00004362911,0.001003047],"genre_scores_gemma":[0.9967212,0.0016166,0.0008727327,0.00007261818,0.00001158134,0.00004731276,0.0001892321,0.000002691283,0.0004659659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000726466,"threshold_uncertainty_score":0.00243026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02056014028559407,"score_gpt":0.2521282510759728,"score_spread":0.2315681107903787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}