{"id":"W2885680330","doi":"10.1158/1538-7445.am2018-ct096","title":"Abstract CT096: Trastuzumab emtansine (T-DM1) + capecitabine in HER2-positive metastatic breast cancer (mBC) and HER2-positive locally advanced (LA)/metastatic gastric cancer (mGC): Results from the phase I/randomized phase II TRAXHER2 study","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Capecitabine; Medicine; Metastatic breast cancer; Internal medicine; Trastuzumab; Gastroenterology; Breast cancer; Cancer; Phases of clinical research; Trastuzumab emtansine; Oncology; Toxicity; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001084066,0.0008652209,0.001266239,0.0004083361,0.0002499605,0.0005260076,0.0006627596,0.0006274717,0.005299635],"category_scores_gemma":[0.0006384699,0.0003294271,0.0007894149,0.0004340699,0.0004926461,0.0005797789,0.0002971573,0.00201746,0.0007815165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007073611,"about_ca_system_score_gemma":0.0009532161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008767321,"about_ca_topic_score_gemma":0.002427674,"domain_scores_codex":[0.9996637,0.0001831454,0.00002270842,0.0000492449,0.00004016052,0.00004095231],"domain_scores_gemma":[0.999546,0.00007934463,0.00007863389,0.00002143808,0.00002468977,0.0002498618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8471471,0.0168507,0.003899211,0.0007346315,0.001160927,0.0002257194,0.00006944664,0.002272617,0.04173123,0.0002878173,0.006563579,0.0790571],"study_design_scores_gemma":[0.6421024,0.3301383,0.01308968,0.00005933261,0.0008202019,0.0004071092,0.00002762458,0.001898617,0.006963772,0.0001659307,0.004301881,0.00002526494],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987061,0.005214274,0.0005082456,0.0006797109,0.0001937218,0.001242913,0.002071982,0.0001678163,0.002860406],"genre_scores_gemma":[0.9862969,0.002873059,0.00123418,0.0006674938,0.0001858968,0.0008999199,0.004121409,0.00003313582,0.003688043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005299635,"threshold_uncertainty_score":0.01772904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05435336479656514,"score_gpt":0.4505987041799581,"score_spread":0.396245339383393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}