{"id":"W2885695485","doi":"10.1016/j.jad.2018.08.025","title":"Low brain-derived neurotrophic factor levels in post-mortem brains of older adults with depression and dementia in a large clinicopathological sample.","year":2018,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Depression (economics); Dementia; Brain-derived neurotrophic factor; Psychology; Neurotrophic factors; Psychiatry; Neuroscience; Clinical psychology; Medicine; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003242325,0.0001495077,0.0002867568,0.0002449734,0.00007120157,0.00001907478,0.000130469,0.0000870333,0.00003119531],"category_scores_gemma":[0.00136199,0.0001014564,0.00006467023,0.0003012236,0.0002100764,0.0003160604,0.00005057418,0.0002983572,6.305639e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002030234,"about_ca_system_score_gemma":0.00006592849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002389544,"about_ca_topic_score_gemma":0.001220097,"domain_scores_codex":[0.9983259,0.0005253093,0.0004066683,0.0002831618,0.0002354025,0.0002235901],"domain_scores_gemma":[0.9987563,0.0005596824,0.0003992818,0.000103765,0.0001152733,0.00006566034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001249313,0.0007729114,0.3462898,0.00003883351,0.000009088903,0.00005663371,0.001913019,0.00004463683,0.6403409,0.00003660211,0.000008197614,0.009240068],"study_design_scores_gemma":[0.003578488,0.002327475,0.8621024,0.0002192346,0.000009228907,0.00003471759,0.0001997948,0.0002310946,0.1310814,0.0001042735,0.000003528537,0.0001083455],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967101,0.00007355353,0.00237007,0.0002966489,0.0001351396,0.0003605707,0.00003029878,0.000005544293,0.00001811293],"genre_scores_gemma":[0.9992529,0.00004602654,0.0001410097,0.0004953865,0.00004374393,0.000005061759,8.940663e-7,0.00001300492,0.000001967412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5158126,"threshold_uncertainty_score":0.413727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0166176892507693,"score_gpt":0.2900022123789967,"score_spread":0.2733845231282274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}