{"id":"W2885758487","doi":"10.3390/ijms19082307","title":"Beyond the Foam Cell: The Role of LXRs in Preventing Atherogenesis","year":2018,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heart and Stroke Foundation; University of Toronto","funders":"Heart and Stroke Foundation of Canada","keywords":"Liver X receptor; Foam cell; Inflammation; Cell biology; Biology; Macrophage; Cell type; Cholesterol; Aorta; Reverse cholesterol transport; Cancer research; Cell; Immunology; Nuclear receptor; Lipoprotein; Medicine; Internal medicine; Endocrinology; Gene; Transcription factor; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005095172,0.0006776365,0.001094135,0.001724996,0.0002764724,0.001053388,0.0007466385,0.001139213,0.003461153],"category_scores_gemma":[0.0005887555,0.00017087,0.0004031995,0.001575964,0.0005644877,0.001457183,0.0006257038,0.002182795,0.002225939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004700513,"about_ca_system_score_gemma":0.0009184967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006563459,"about_ca_topic_score_gemma":0.0009747545,"domain_scores_codex":[0.9998395,0.00003437013,0.00002030743,0.00002894338,0.00005940099,0.00001751999],"domain_scores_gemma":[0.9997776,0.00009328055,0.00002597996,0.000008891945,0.00006727581,0.00002700093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009517043,0.00009044787,0.0001368539,0.0130051,0.00006350373,0.0001923367,0.00008522142,0.0003068836,0.002130257,0.007665855,0.03135525,0.944873],"study_design_scores_gemma":[0.00001380093,0.00009820615,0.0004425606,0.001968539,0.00003990904,0.0006805896,0.00004190101,0.00004782672,0.000363821,0.002577329,0.9937147,0.00001068307],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001140038,0.9982148,0.0001144275,0.0004472233,0.0002992792,0.000003779721,0.00001261416,0.000007620594,0.0007862862],"genre_scores_gemma":[0.0006006453,0.9982514,0.0001254166,0.0001999569,0.0002220984,0.000004600814,0.00001679168,0.000001449347,0.000577646],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003461153,"threshold_uncertainty_score":0.01157868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0252962371796451,"score_gpt":0.3402576942239869,"score_spread":0.3149614570443418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}