{"id":"W2885789567","doi":"10.1002/path.5146","title":"Multilevel heterogeneity of mitochondrial respiratory chain deficiency","year":2018,"lang":"en","type":"letter","venue":"The Journal of Pathology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Medical Research Council Canada; Wellcome Trust","keywords":"Mitochondrial DNA; Cytochrome c oxidase; Mitochondrion; Respiratory chain; Mitochondrial disease; Mitochondrial respiratory chain; Biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009426111,0.0003205957,0.0006186408,0.0001964596,0.00009669293,0.000007701322,0.0008635431,0.001337067,0.0001149961],"category_scores_gemma":[0.0005903474,0.0002197506,0.0004042888,0.00008662183,0.0006644143,0.000003883672,0.0001959847,0.001120422,0.00002840061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002030877,"about_ca_system_score_gemma":0.0002296923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004166429,"about_ca_topic_score_gemma":0.00001521078,"domain_scores_codex":[0.9966165,0.001422535,0.0009666833,0.0003062128,0.0003079941,0.0003800048],"domain_scores_gemma":[0.9970286,0.000121615,0.001455199,0.0007760221,0.0005566988,0.00006186753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003312956,0.0000321955,0.00005699096,0.00002690273,0.00004857218,0.0001853367,0.00007982406,0.000008288825,0.5220354,0.000004113022,0.4769939,0.0001971525],"study_design_scores_gemma":[0.001226887,0.003270207,0.0001452521,0.00003867625,0.0002109132,0.003608612,0.00003068089,0.000002635876,0.1652301,0.0001343219,0.8258156,0.0002861728],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.8598642,0.00837263,0.03928455,0.05895542,0.0300464,0.001093583,0.0004265154,0.00002323566,0.001933443],"genre_scores_gemma":[0.05538617,0.001513986,0.01048175,0.8124161,0.1139705,0.00003674277,0.0003231015,0.0003699553,0.0055016],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.804478,"threshold_uncertainty_score":0.9999594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03060284223808253,"score_gpt":0.2785168303466883,"score_spread":0.2479139881086058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}